Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma
We present a case of highly elevated tenfold rise of serum chromogranin A in a young, morbidly obese, hypertensive female being investigated for pancreatic mass, weight loss, and elevated ESR. Following extensive noninvasive investigations, an ultrasound-guided pancreatic biopsy confirmed benign hae...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2011/342480 |
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| author | Usman Hammawa Malabu Rozemary Karamatic Gillian Mahy Kunwarjit Singh Sangla |
| author_facet | Usman Hammawa Malabu Rozemary Karamatic Gillian Mahy Kunwarjit Singh Sangla |
| author_sort | Usman Hammawa Malabu |
| collection | DOAJ |
| description | We present a case of highly elevated tenfold rise of serum chromogranin A in a young, morbidly obese, hypertensive female being investigated for pancreatic mass, weight loss, and elevated ESR. Following extensive noninvasive investigations, an ultrasound-guided pancreatic biopsy confirmed benign haemorrhagic cyst. A clue to the etiology of the hyperchromogranin A was the elevated serum gastrin level leading to suspicion of proton pump inhibitor administration confirmed by admittance to its use. Withdrawal of the medication led to dramatic resolution of the neuroendocrine tumor marker. |
| format | Article |
| id | doaj-art-21894fa5393c44bbaa49a5f635c3c3be |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-21894fa5393c44bbaa49a5f635c3c3be2025-02-03T05:46:21ZengWileyCase Reports in Endocrinology2090-65012090-651X2011-01-01201110.1155/2011/342480342480Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic IncidentalomaUsman Hammawa Malabu0Rozemary Karamatic1Gillian Mahy2Kunwarjit Singh Sangla3Department of Endocrinology, Townsville Hospital, 100 Angus Smith Drive, Douglas QLD 4814, AustraliaDepartment of Gastroenterology, The Townsville Hospital, 100 Angus Smith Drive, Douglas QLD 4814, AustraliaDepartment of Gastroenterology, The Townsville Hospital, 100 Angus Smith Drive, Douglas QLD 4814, AustraliaDepartment of Endocrinology, Townsville Hospital, 100 Angus Smith Drive, Douglas QLD 4814, AustraliaWe present a case of highly elevated tenfold rise of serum chromogranin A in a young, morbidly obese, hypertensive female being investigated for pancreatic mass, weight loss, and elevated ESR. Following extensive noninvasive investigations, an ultrasound-guided pancreatic biopsy confirmed benign haemorrhagic cyst. A clue to the etiology of the hyperchromogranin A was the elevated serum gastrin level leading to suspicion of proton pump inhibitor administration confirmed by admittance to its use. Withdrawal of the medication led to dramatic resolution of the neuroendocrine tumor marker.http://dx.doi.org/10.1155/2011/342480 |
| spellingShingle | Usman Hammawa Malabu Rozemary Karamatic Gillian Mahy Kunwarjit Singh Sangla Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma Case Reports in Endocrinology |
| title | Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma |
| title_full | Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma |
| title_fullStr | Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma |
| title_full_unstemmed | Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma |
| title_short | Malignant Range Elevation of Serum Chromogranin A due to Inadvertent Use of Proton Pump Inhibitor in a Subject with Pancreatic Incidentaloma |
| title_sort | malignant range elevation of serum chromogranin a due to inadvertent use of proton pump inhibitor in a subject with pancreatic incidentaloma |
| url | http://dx.doi.org/10.1155/2011/342480 |
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