Cinnamon in Anticancer Armamentarium: A Molecular Approach
In recent years, natural bioactive components draw a major attention for their potent anticarcinogenic activity. Cinnamon, one of the traditional spices, most frequently used in almost every household of tropical countries has got enormous efficacy to combat cancer. Cinnamon as a whole and/or its ac...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Journal of Toxicology |
| Online Access: | http://dx.doi.org/10.1155/2018/8978731 |
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| author | Anindita Dutta Anindita Chakraborty |
| author_facet | Anindita Dutta Anindita Chakraborty |
| author_sort | Anindita Dutta |
| collection | DOAJ |
| description | In recent years, natural bioactive components draw a major attention for their potent anticarcinogenic activity. Cinnamon, one of the traditional spices, most frequently used in almost every household of tropical countries has got enormous efficacy to combat cancer. Cinnamon as a whole and/or its active components exhibited significant antineoplastic activity in different types of cancer. This review has been carried out to elicit the molecular mechanisms of action of cinnamon and its components on oncogenic regulators and related pathways. Web sites of Google Scholar, Medline, and PubMed were searched for articles written in English and published in peer-reviewed journals from 2003 to 2017. The anticarcinogenic potential of cinnamon varies with the type of cancer and also depends on the administered active compound individually or in combination with some chemicals or even extract of cinnamon as a whole. Some of its active components exert chemosensitization of well-known anticancer drugs. These outstanding properties of this spice necessitate its incorporation in both pharmaceuticals and nutraceuticals to explore possibilities of formulation of novel drug from this spice for treatment and prevention strategy of cancer. |
| format | Article |
| id | doaj-art-217e4327751a4a8f9fd3635eedfbc4d7 |
| institution | OA Journals |
| issn | 1687-8191 1687-8205 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Toxicology |
| spelling | doaj-art-217e4327751a4a8f9fd3635eedfbc4d72025-08-20T02:03:58ZengWileyJournal of Toxicology1687-81911687-82052018-01-01201810.1155/2018/89787318978731Cinnamon in Anticancer Armamentarium: A Molecular ApproachAnindita Dutta0Anindita Chakraborty1UGC-DAE Consortium for Scientific Research, Kolkata Centre, Sector-III, Block-LB-8, Salt Lake, Kolkata, West Bengal 700106, IndiaUGC-DAE Consortium for Scientific Research, Kolkata Centre, Sector-III, Block-LB-8, Salt Lake, Kolkata, West Bengal 700106, IndiaIn recent years, natural bioactive components draw a major attention for their potent anticarcinogenic activity. Cinnamon, one of the traditional spices, most frequently used in almost every household of tropical countries has got enormous efficacy to combat cancer. Cinnamon as a whole and/or its active components exhibited significant antineoplastic activity in different types of cancer. This review has been carried out to elicit the molecular mechanisms of action of cinnamon and its components on oncogenic regulators and related pathways. Web sites of Google Scholar, Medline, and PubMed were searched for articles written in English and published in peer-reviewed journals from 2003 to 2017. The anticarcinogenic potential of cinnamon varies with the type of cancer and also depends on the administered active compound individually or in combination with some chemicals or even extract of cinnamon as a whole. Some of its active components exert chemosensitization of well-known anticancer drugs. These outstanding properties of this spice necessitate its incorporation in both pharmaceuticals and nutraceuticals to explore possibilities of formulation of novel drug from this spice for treatment and prevention strategy of cancer.http://dx.doi.org/10.1155/2018/8978731 |
| spellingShingle | Anindita Dutta Anindita Chakraborty Cinnamon in Anticancer Armamentarium: A Molecular Approach Journal of Toxicology |
| title | Cinnamon in Anticancer Armamentarium: A Molecular Approach |
| title_full | Cinnamon in Anticancer Armamentarium: A Molecular Approach |
| title_fullStr | Cinnamon in Anticancer Armamentarium: A Molecular Approach |
| title_full_unstemmed | Cinnamon in Anticancer Armamentarium: A Molecular Approach |
| title_short | Cinnamon in Anticancer Armamentarium: A Molecular Approach |
| title_sort | cinnamon in anticancer armamentarium a molecular approach |
| url | http://dx.doi.org/10.1155/2018/8978731 |
| work_keys_str_mv | AT aninditadutta cinnamoninanticancerarmamentariumamolecularapproach AT aninditachakraborty cinnamoninanticancerarmamentariumamolecularapproach |