Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube
Solid dosage forms like modified release and enteric coated formulations are considered inappropriate for nasogastric feeding tube (NGFT) administration due to varying pharmacokinetics which could lead to inadequate therapeutic responses or toxicity. An analysis was conducted to assess the...
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| Format: | Article |
| Language: | English |
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Krupanidhi College of Pharmacy
2023-12-01
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| Series: | Journal of Pharmaceutical Research |
| Online Access: | https://jopcr.com/articles/importance-of-appropriate-medication-administration-in-patients-with-nasogastric-feeding-tube |
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| author | L A Pradeep Rajkumar Sujith J Chandy Heber Rew Bright V J Hema Jiji Judith Basker K Gunaraj |
| author_facet | L A Pradeep Rajkumar Sujith J Chandy Heber Rew Bright V J Hema Jiji Judith Basker K Gunaraj |
| author_sort | L A Pradeep Rajkumar |
| collection | DOAJ |
| description | Solid dosage forms like modified release and enteric coated formulations are considered inappropriate for nasogastric feeding tube (NGFT) administration due to varying pharmacokinetics which could lead to inadequate therapeutic responses or toxicity. An analysis was conducted to assess the appropriateness of prescribed medicines for NGFT administration in hospital inpatients so that physicians can be sensitized to the importance of this. In this cross-sectional study conducted in a large tertiary care centre, prescription data of in-patients with nasogastric feeding tube (NGFT) were retrieved through electronic pharmacy transactions. Adult patients who were admitted in the hospital for more than one day and were dispensed a NGFT were included. The appropriateness of medicines administered through NGFT was assessed using standard published literature. Details of medicines that were categorized as inappropriate were collated and analysed. In case of inappropriate prescribing, availability of appropriate dosage forms was also determined. A total of 510 patients were found eligible for analyses. Majority of the patients were dispensed at least one inappropriate dosage form. Among the dispensed oral solid dosage forms, 16.38% were found to be inappropriate for NGFT administration. Of these, 21.41% were dispensed on same day as the NGFT, 34.67% were dispensed before the NGFT and were continued throughout the hospital stay and 43.92% were dispensed within or after 24 hours of NGFT dispensation. These findings will improve awareness among healthcare professionals about the need for appropriate administration of oral formulations in patients intubated with NGFT. Keywords: Inappropriate Dosage Forms, Nasogastric Feeding Tube, Appropriate Dosage Forms, Modified Release Formulations |
| format | Article |
| id | doaj-art-217d9fae6064408f8537a982cfccb917 |
| institution | Kabale University |
| issn | 0973-7200 2454-8405 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Krupanidhi College of Pharmacy |
| record_format | Article |
| series | Journal of Pharmaceutical Research |
| spelling | doaj-art-217d9fae6064408f8537a982cfccb9172025-08-21T09:34:08ZengKrupanidhi College of PharmacyJournal of Pharmaceutical Research0973-72002454-84052023-12-0122315215710.18579/jopcr/v22.3.23.46Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding TubeL A Pradeep RajkumarSujith J ChandyHeber Rew BrightV J Hema JijiJudith BaskerK Gunaraj Solid dosage forms like modified release and enteric coated formulations are considered inappropriate for nasogastric feeding tube (NGFT) administration due to varying pharmacokinetics which could lead to inadequate therapeutic responses or toxicity. An analysis was conducted to assess the appropriateness of prescribed medicines for NGFT administration in hospital inpatients so that physicians can be sensitized to the importance of this. In this cross-sectional study conducted in a large tertiary care centre, prescription data of in-patients with nasogastric feeding tube (NGFT) were retrieved through electronic pharmacy transactions. Adult patients who were admitted in the hospital for more than one day and were dispensed a NGFT were included. The appropriateness of medicines administered through NGFT was assessed using standard published literature. Details of medicines that were categorized as inappropriate were collated and analysed. In case of inappropriate prescribing, availability of appropriate dosage forms was also determined. A total of 510 patients were found eligible for analyses. Majority of the patients were dispensed at least one inappropriate dosage form. Among the dispensed oral solid dosage forms, 16.38% were found to be inappropriate for NGFT administration. Of these, 21.41% were dispensed on same day as the NGFT, 34.67% were dispensed before the NGFT and were continued throughout the hospital stay and 43.92% were dispensed within or after 24 hours of NGFT dispensation. These findings will improve awareness among healthcare professionals about the need for appropriate administration of oral formulations in patients intubated with NGFT. Keywords: Inappropriate Dosage Forms, Nasogastric Feeding Tube, Appropriate Dosage Forms, Modified Release Formulationshttps://jopcr.com/articles/importance-of-appropriate-medication-administration-in-patients-with-nasogastric-feeding-tube |
| spellingShingle | L A Pradeep Rajkumar Sujith J Chandy Heber Rew Bright V J Hema Jiji Judith Basker K Gunaraj Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube Journal of Pharmaceutical Research |
| title | Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube |
| title_full | Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube |
| title_fullStr | Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube |
| title_full_unstemmed | Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube |
| title_short | Importance of Appropriate Medication Administration in Patients with Nasogastric Feeding Tube |
| title_sort | importance of appropriate medication administration in patients with nasogastric feeding tube |
| url | https://jopcr.com/articles/importance-of-appropriate-medication-administration-in-patients-with-nasogastric-feeding-tube |
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