Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles

The aquaculture industry is in dire need of novel feed ingredients that can improve the health and welfare of farmed fish and shrimp. Zooplankton are natural and underutilized marine resources with the potential to be part of a nutritional solution. The aim of this study was to determine the health...

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Main Authors: Isak Bøgwald, Alice Marie Pedersen, Jorge Dias, Sileshi Gizachew Wubshet, Karl-Erik Eilertsen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Aquaculture Nutrition
Online Access:http://dx.doi.org/10.1155/anu/5531437
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author Isak Bøgwald
Alice Marie Pedersen
Jorge Dias
Sileshi Gizachew Wubshet
Karl-Erik Eilertsen
author_facet Isak Bøgwald
Alice Marie Pedersen
Jorge Dias
Sileshi Gizachew Wubshet
Karl-Erik Eilertsen
author_sort Isak Bøgwald
collection DOAJ
description The aquaculture industry is in dire need of novel feed ingredients that can improve the health and welfare of farmed fish and shrimp. Zooplankton are natural and underutilized marine resources with the potential to be part of a nutritional solution. The aim of this study was to determine the health effects for European sea bass juveniles fed diets with a protein hydrolysate from the zooplankton species Calanus finmarchicus, a novel raw material for feed ingredients. Calanus hydrolysate (CH) was benchmarked using fish hydrolysates as controls at inclusion rates of 3%–4%, depending on the protein content for each of the hydrolysates to allow equivalent protein levels in the diets. The initial feeding trial was 84 days, with an additional week to perform an inflammatory challenge with a UV-inactivated bacterium. Fish receiving diets with CH inclusion were associated with lower levels of hepatic protein carbonyls, a lower level of calprotectin and higher levels of mucins compared to the control hydrolysate diets. No statistically significant differences among the diets for the biomarkers related to the inflammatory challenge were observed. The study showed that dietary inclusion of CH has the potential to reduce oxidative stress and increase intestinal health, thus, improving the health of European sea bass juveniles. These health-promoting effects, combined with the sustainable origin of C. finmarchicus highlight the potential of CH as a novel functional ingredient for future aquaculture feeds. Its use could contribute to reduced reliance on traditional fishmeal sources, thereby, supporting more sustainable and resilient aquaculture practices.
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institution Kabale University
issn 1365-2095
language English
publishDate 2025-01-01
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series Aquaculture Nutrition
spelling doaj-art-21790b1dff3e448e9270c110b6db09792025-08-20T03:41:57ZengWileyAquaculture Nutrition1365-20952025-01-01202510.1155/anu/5531437Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) JuvenilesIsak Bøgwald0Alice Marie Pedersen1Jorge Dias2Sileshi Gizachew Wubshet3Karl-Erik Eilertsen4The Norwegian College of Fishery ScienceCalanus ASSPAROS LdaNofima AS – Norwegian Institute of FoodThe Norwegian College of Fishery ScienceThe aquaculture industry is in dire need of novel feed ingredients that can improve the health and welfare of farmed fish and shrimp. Zooplankton are natural and underutilized marine resources with the potential to be part of a nutritional solution. The aim of this study was to determine the health effects for European sea bass juveniles fed diets with a protein hydrolysate from the zooplankton species Calanus finmarchicus, a novel raw material for feed ingredients. Calanus hydrolysate (CH) was benchmarked using fish hydrolysates as controls at inclusion rates of 3%–4%, depending on the protein content for each of the hydrolysates to allow equivalent protein levels in the diets. The initial feeding trial was 84 days, with an additional week to perform an inflammatory challenge with a UV-inactivated bacterium. Fish receiving diets with CH inclusion were associated with lower levels of hepatic protein carbonyls, a lower level of calprotectin and higher levels of mucins compared to the control hydrolysate diets. No statistically significant differences among the diets for the biomarkers related to the inflammatory challenge were observed. The study showed that dietary inclusion of CH has the potential to reduce oxidative stress and increase intestinal health, thus, improving the health of European sea bass juveniles. These health-promoting effects, combined with the sustainable origin of C. finmarchicus highlight the potential of CH as a novel functional ingredient for future aquaculture feeds. Its use could contribute to reduced reliance on traditional fishmeal sources, thereby, supporting more sustainable and resilient aquaculture practices.http://dx.doi.org/10.1155/anu/5531437
spellingShingle Isak Bøgwald
Alice Marie Pedersen
Jorge Dias
Sileshi Gizachew Wubshet
Karl-Erik Eilertsen
Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
Aquaculture Nutrition
title Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
title_full Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
title_fullStr Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
title_full_unstemmed Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
title_short Dietary Protein Hydrolysate From Calanus finmarchicus Reduces Oxidative Stress and Increases Intestinal Health in European Sea Bass (Dicentrarchus labrax) Juveniles
title_sort dietary protein hydrolysate from calanus finmarchicus reduces oxidative stress and increases intestinal health in european sea bass dicentrarchus labrax juveniles
url http://dx.doi.org/10.1155/anu/5531437
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