Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess

Abstract High levels of nitrates and nitrites not only threaten aquatic ecosystems and drinking water safety but also impair the biodegradation efficiency of industrial wastewater. In this study, micro-nano-MoS2-1013 (0.04 g/L) enhanced denitrification by 56.9% and 29.6% in steel pickling and meat p...

Full description

Saved in:
Bibliographic Details
Main Authors: Zhaozhou Peng, Jiangyuan Sun, Panpan Li, Junzhang Li, Chen Shen, Xia Tian, Jing Lian, Phathutshedzo Khangale, Xiangjing Zhang, Tonderayi Matambo, Diane Hildebrandt, Xinying Liu, Shouxin Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:npj Clean Water
Online Access:https://doi.org/10.1038/s41545-025-00494-y
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849334072152686592
author Zhaozhou Peng
Jiangyuan Sun
Panpan Li
Junzhang Li
Chen Shen
Xia Tian
Jing Lian
Phathutshedzo Khangale
Xiangjing Zhang
Tonderayi Matambo
Diane Hildebrandt
Xinying Liu
Shouxin Liu
author_facet Zhaozhou Peng
Jiangyuan Sun
Panpan Li
Junzhang Li
Chen Shen
Xia Tian
Jing Lian
Phathutshedzo Khangale
Xiangjing Zhang
Tonderayi Matambo
Diane Hildebrandt
Xinying Liu
Shouxin Liu
author_sort Zhaozhou Peng
collection DOAJ
description Abstract High levels of nitrates and nitrites not only threaten aquatic ecosystems and drinking water safety but also impair the biodegradation efficiency of industrial wastewater. In this study, micro-nano-MoS2-1013 (0.04 g/L) enhanced denitrification by 56.9% and 29.6% in steel pickling and meat processing wastewaters, respectively, and improved chemical oxygen demand (COD) removal by 136.7% in refinery cooling wastewater under continuous-flow conditions using a 3.5 L upflow anaerobic sludge blanket (UASB) reactor. The catalytic effect of micro-nano-MoS2 on denitrification was achieved by stimulating an increase in the abundance of denitrification genes and the transcript levels of narL (93.82 times), narG (16.34 times), and nirK (12.27 times) within the bacterial cells, which led to an increase in the expression levels of denitrifying enzymes. These findings have significant implications for the design and optimization of biodegradation processes and bio-denitrification systems, particularly for the treatment of high-concentration nitrate wastewater.
format Article
id doaj-art-21669ec7e82e48e1a824fdfde9f885ed
institution Kabale University
issn 2059-7037
language English
publishDate 2025-07-01
publisher Nature Portfolio
record_format Article
series npj Clean Water
spelling doaj-art-21669ec7e82e48e1a824fdfde9f885ed2025-08-20T03:45:40ZengNature Portfolionpj Clean Water2059-70372025-07-01811910.1038/s41545-025-00494-yBoosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocessZhaozhou Peng0Jiangyuan Sun1Panpan Li2Junzhang Li3Chen Shen4Xia Tian5Jing Lian6Phathutshedzo Khangale7Xiangjing Zhang8Tonderayi Matambo9Diane Hildebrandt10Xinying Liu11Shouxin Liu12Hebei University of Science and TechnologyHebei University of Science and TechnologyHebei University of Science and TechnologyHebei University of Science and TechnologyHebei University of Science and TechnologyHebei University of Science and TechnologyHebei University of Science and TechnologyUniversity of South AfricaHebei University of Science and TechnologyUniversity of South AfricaDepartment of Chemical and Biochemical Engineering, Rutgers UniversityUniversity of South AfricaHebei University of Science and TechnologyAbstract High levels of nitrates and nitrites not only threaten aquatic ecosystems and drinking water safety but also impair the biodegradation efficiency of industrial wastewater. In this study, micro-nano-MoS2-1013 (0.04 g/L) enhanced denitrification by 56.9% and 29.6% in steel pickling and meat processing wastewaters, respectively, and improved chemical oxygen demand (COD) removal by 136.7% in refinery cooling wastewater under continuous-flow conditions using a 3.5 L upflow anaerobic sludge blanket (UASB) reactor. The catalytic effect of micro-nano-MoS2 on denitrification was achieved by stimulating an increase in the abundance of denitrification genes and the transcript levels of narL (93.82 times), narG (16.34 times), and nirK (12.27 times) within the bacterial cells, which led to an increase in the expression levels of denitrifying enzymes. These findings have significant implications for the design and optimization of biodegradation processes and bio-denitrification systems, particularly for the treatment of high-concentration nitrate wastewater.https://doi.org/10.1038/s41545-025-00494-y
spellingShingle Zhaozhou Peng
Jiangyuan Sun
Panpan Li
Junzhang Li
Chen Shen
Xia Tian
Jing Lian
Phathutshedzo Khangale
Xiangjing Zhang
Tonderayi Matambo
Diane Hildebrandt
Xinying Liu
Shouxin Liu
Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
npj Clean Water
title Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
title_full Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
title_fullStr Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
title_full_unstemmed Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
title_short Boosting industrial bio-denitrification through gene activation: the micro-nano-MoS2 enhanced bioprocess
title_sort boosting industrial bio denitrification through gene activation the micro nano mos2 enhanced bioprocess
url https://doi.org/10.1038/s41545-025-00494-y
work_keys_str_mv AT zhaozhoupeng boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT jiangyuansun boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT panpanli boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT junzhangli boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT chenshen boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT xiatian boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT jinglian boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT phathutshedzokhangale boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT xiangjingzhang boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT tonderayimatambo boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT dianehildebrandt boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT xinyingliu boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess
AT shouxinliu boostingindustrialbiodenitrificationthroughgeneactivationthemicronanomos2enhancedbioprocess