Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights
Objective: Type 1 diabetes (T1D) is a common, chronic, systemic disease in children and adolescents, and its incidence globally increases annually. This study aimed to determine the incidence, diagnostic features, and presentation characteristics of T1D in children and adolescents during the pandem...
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| Language: | English |
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Aydın Pediatric Society
2025-06-01
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| Series: | Trends in Pediatrics |
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| Online Access: | https://trendspediatrics.com/article/view/193 |
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| author | Yasemin Denkboy Öngen Özlem Kara Emine Demet Akbaş Güven Özkaya Erdal Eren |
| author_facet | Yasemin Denkboy Öngen Özlem Kara Emine Demet Akbaş Güven Özkaya Erdal Eren |
| author_sort | Yasemin Denkboy Öngen |
| collection | DOAJ |
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Objective: Type 1 diabetes (T1D) is a common, chronic, systemic disease in children and adolescents, and its incidence globally increases annually. This study aimed to determine the incidence, diagnostic features, and presentation characteristics of T1D in children and adolescents during the pandemic period in Bursa Province, Turkey.
Method: This study included children under 18 with newly diagnosed T1D who consulted the Pediatric Endocrinology clinics of 3 tertiary hospitals in the city center of Bursa between January 1, 2015, and December 31, 2022. Nine hundred twenty-one pediatric patients were included in the study. The patients were divided into four groups according to age: Group 1, 0-4.9 years; Group 2, 5-9.9 years; Group 3, 10-14.9 years; and Group 4, 15-18 years.
Results: Of the patients, 48.6% were female, and 51.4% were male. The median age at diagnosis was 9.23 years, with a significant age difference between genders. The highest incidence was observed in children aged 10-14.9 years. Moreover, two peaks were detected: 10-14.9 years in males and 5-9.9 years in females. The mean annual incidence was 3.8/100,000, peaking in 2017. During the COVID-19 pandemic, a temporary decline in diagnoses was noted, followed by an increase. Diabetic ketoacidosis (DKA) rates showed a significant rise over time, particularly in severe DKA cases during the pandemic.
Conclusion: This study provides the first comprehensive analysis of the rate of newly diagnosed T1D in children and adolescents in Bursa Province. Additionally, the study evaluated age, gender, and seasonal patterns of initial diagnoses, with global trends constantly. The incidence of T1D and the rate and severity of DKA at presentation were affected during the COVID-19 pandemic, causing lockdowns and healthcare avoidance.
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| format | Article |
| id | doaj-art-215eb350e6a744df807ca889eb7fea80 |
| institution | Kabale University |
| issn | 2792-0429 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Aydın Pediatric Society |
| record_format | Article |
| series | Trends in Pediatrics |
| spelling | doaj-art-215eb350e6a744df807ca889eb7fea802025-08-20T03:31:20ZengAydın Pediatric SocietyTrends in Pediatrics2792-04292025-06-016210.59213/TP.2025.193Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insightsYasemin Denkboy Öngen0https://orcid.org/0000-0002-5657-4260Özlem Kara1https://orcid.org/0000-0003-0915-5546Emine Demet Akbaş2https://orcid.org/0000-0002-5746-6835Güven Özkaya3https://orcid.org/0000-0003-0297-846XErdal Eren4https://orcid.org/0000-0002-1684-1053Department of Pediatric Endocrinology, Faculty of Medicine, Bursa Uludağ University, Bursa, TürkiyeDepartment of Pediatric Endocrinology, Bursa Yüksek İhtisas Training and Research Hospital, Bursa, TürkiyeDepartment of Pediatric Endocrinology, Bursa Dörtçelik Children Hospital, Bursa, TürkiyeDepartment of Biostatistics, Faculty of Medicine, Bursa Uludağ University, Bursa, TürkiyeDepartment of Pediatric Endocrinology, Faculty of Medicine, Bursa Uludağ University, Bursa, Türkiye Objective: Type 1 diabetes (T1D) is a common, chronic, systemic disease in children and adolescents, and its incidence globally increases annually. This study aimed to determine the incidence, diagnostic features, and presentation characteristics of T1D in children and adolescents during the pandemic period in Bursa Province, Turkey. Method: This study included children under 18 with newly diagnosed T1D who consulted the Pediatric Endocrinology clinics of 3 tertiary hospitals in the city center of Bursa between January 1, 2015, and December 31, 2022. Nine hundred twenty-one pediatric patients were included in the study. The patients were divided into four groups according to age: Group 1, 0-4.9 years; Group 2, 5-9.9 years; Group 3, 10-14.9 years; and Group 4, 15-18 years. Results: Of the patients, 48.6% were female, and 51.4% were male. The median age at diagnosis was 9.23 years, with a significant age difference between genders. The highest incidence was observed in children aged 10-14.9 years. Moreover, two peaks were detected: 10-14.9 years in males and 5-9.9 years in females. The mean annual incidence was 3.8/100,000, peaking in 2017. During the COVID-19 pandemic, a temporary decline in diagnoses was noted, followed by an increase. Diabetic ketoacidosis (DKA) rates showed a significant rise over time, particularly in severe DKA cases during the pandemic. Conclusion: This study provides the first comprehensive analysis of the rate of newly diagnosed T1D in children and adolescents in Bursa Province. Additionally, the study evaluated age, gender, and seasonal patterns of initial diagnoses, with global trends constantly. The incidence of T1D and the rate and severity of DKA at presentation were affected during the COVID-19 pandemic, causing lockdowns and healthcare avoidance. https://trendspediatrics.com/article/view/193BursaCOVID-19incidenceketoacidosistype 1 diabetesnewly diagnosed type 1 diabetes |
| spellingShingle | Yasemin Denkboy Öngen Özlem Kara Emine Demet Akbaş Güven Özkaya Erdal Eren Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights Trends in Pediatrics Bursa COVID-19 incidence ketoacidosis type 1 diabetes newly diagnosed type 1 diabetes |
| title | Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights |
| title_full | Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights |
| title_fullStr | Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights |
| title_full_unstemmed | Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights |
| title_short | Trends in type 1 diabetes incidence among children and adolescents in Bursa (2015-2022): impact of the COVID-19 pandemic and demographic insights |
| title_sort | trends in type 1 diabetes incidence among children and adolescents in bursa 2015 2022 impact of the covid 19 pandemic and demographic insights |
| topic | Bursa COVID-19 incidence ketoacidosis type 1 diabetes newly diagnosed type 1 diabetes |
| url | https://trendspediatrics.com/article/view/193 |
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