Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review

In this review paper, the definition of the tissue engineering (TE) was comprehensively explored towards scaffold fabrication techniques and applications. Scaffold properties and features in TE, biological aspects, scaffold material composition, scaffold structural requirements, and old and current...

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Main Authors: Abdalla Eltom, Gaoyan Zhong, Ameen Muhammad
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Advances in Materials Science and Engineering
Online Access:http://dx.doi.org/10.1155/2019/3429527
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author Abdalla Eltom
Gaoyan Zhong
Ameen Muhammad
author_facet Abdalla Eltom
Gaoyan Zhong
Ameen Muhammad
author_sort Abdalla Eltom
collection DOAJ
description In this review paper, the definition of the tissue engineering (TE) was comprehensively explored towards scaffold fabrication techniques and applications. Scaffold properties and features in TE, biological aspects, scaffold material composition, scaffold structural requirements, and old and current manufacturing technologies were reported and discussed. In almost all the reviewed reports, the TE definition denotes renewal, development, and repairs of damaged tissues caused by various factors such as disease, injury, or congenital disabilities. TE is multidisciplinary that combines biology, biochemistry, clinical medicine, and materials science whose application in cellular systems such as organ transplantation serves as a delivery vehicle for cells and drug. According to the previous literature and this review, the scaffold fabrication techniques can be classified into two main categories: conventional and modern techniques. These TE fabrication techniques are applied in the scaffold building which later on are used in tissue and organ structure. The benefits and drawbacks of each of the fabrication techniques have been described in conjunction with current areas of research devoted to deal with some of the challenges. To figure out, the highlighted aspects aimed to define the advancements and challenges that should be addressed in the scaffold design for tissue engineering. Additionally, this study provides an excellent review of original numerical approaches focused on mechanical characteristics that can be helpful in the scaffold design assessment in the analysis of scaffold parameters in tissue engineering.
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spelling doaj-art-215e2b183dd74722bcbb6a693445f09e2025-08-20T02:03:57ZengWileyAdvances in Materials Science and Engineering1687-84341687-84422019-01-01201910.1155/2019/34295273429527Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A ReviewAbdalla Eltom0Gaoyan Zhong1Ameen Muhammad2College of Engineering, Nanjing Agricultural University, Nanjing 210031, ChinaCollege of Engineering, Nanjing Agricultural University, Nanjing 210031, ChinaCollege of Engineering, Nanjing Agricultural University, Nanjing 210031, ChinaIn this review paper, the definition of the tissue engineering (TE) was comprehensively explored towards scaffold fabrication techniques and applications. Scaffold properties and features in TE, biological aspects, scaffold material composition, scaffold structural requirements, and old and current manufacturing technologies were reported and discussed. In almost all the reviewed reports, the TE definition denotes renewal, development, and repairs of damaged tissues caused by various factors such as disease, injury, or congenital disabilities. TE is multidisciplinary that combines biology, biochemistry, clinical medicine, and materials science whose application in cellular systems such as organ transplantation serves as a delivery vehicle for cells and drug. According to the previous literature and this review, the scaffold fabrication techniques can be classified into two main categories: conventional and modern techniques. These TE fabrication techniques are applied in the scaffold building which later on are used in tissue and organ structure. The benefits and drawbacks of each of the fabrication techniques have been described in conjunction with current areas of research devoted to deal with some of the challenges. To figure out, the highlighted aspects aimed to define the advancements and challenges that should be addressed in the scaffold design for tissue engineering. Additionally, this study provides an excellent review of original numerical approaches focused on mechanical characteristics that can be helpful in the scaffold design assessment in the analysis of scaffold parameters in tissue engineering.http://dx.doi.org/10.1155/2019/3429527
spellingShingle Abdalla Eltom
Gaoyan Zhong
Ameen Muhammad
Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
Advances in Materials Science and Engineering
title Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
title_full Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
title_fullStr Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
title_full_unstemmed Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
title_short Scaffold Techniques and Designs in Tissue Engineering Functions and Purposes: A Review
title_sort scaffold techniques and designs in tissue engineering functions and purposes a review
url http://dx.doi.org/10.1155/2019/3429527
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AT gaoyanzhong scaffoldtechniquesanddesignsintissueengineeringfunctionsandpurposesareview
AT ameenmuhammad scaffoldtechniquesanddesignsintissueengineeringfunctionsandpurposesareview