The C2238/αANP variant is a negative modulator of both viability and function of coronary artery smooth muscle cells.

The C2238/αANP variant is a negative modulator of both viability and function of coronary artery smooth muscle cells.

<h4>Background</h4>Abnormalities of vascular smooth muscle cells (VSMCs) contribute to development of vascular disease. Atrial natriuretic peptide (ANP) exerts important effects on VSMCs. A common ANP molecular variant (T2238C/αANP) has recently emerged as a novel vascular risk factor.&l...

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Bibliographic Details
Main Authors: Speranza Rubattu, Simona Marchitti, Franca Bianchi, Sara Di Castro, Rosita Stanzione, Maria Cotugno, Cristina Bozzao, Sebastiano Sciarretta, Massimo Volpe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113108&type=printable
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