Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals
Wild aquatic birds are the primary hosts of H13 avian influenza viruses (AIVs). Herein, we performed a genetic analysis of two H13 AIVs isolated from wild birds in China and evaluated their infection potential in poultry to further explore the potential for transmission from wild aquatic birds to po...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2023-12-01
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| Series: | Emerging Microbes and Infections |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/22221751.2023.2184177 |
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| author | Weiyang Sun Menglin Zhao Zhijun Yu Yuanguo Li Xinghai Zhang Na Feng Tiecheng Wang Hongmei Wang Hongbin He Yongkun Zhao Songtao Yang Xianzhu Xia Yuwei Gao |
| author_facet | Weiyang Sun Menglin Zhao Zhijun Yu Yuanguo Li Xinghai Zhang Na Feng Tiecheng Wang Hongmei Wang Hongbin He Yongkun Zhao Songtao Yang Xianzhu Xia Yuwei Gao |
| author_sort | Weiyang Sun |
| collection | DOAJ |
| description | Wild aquatic birds are the primary hosts of H13 avian influenza viruses (AIVs). Herein, we performed a genetic analysis of two H13 AIVs isolated from wild birds in China and evaluated their infection potential in poultry to further explore the potential for transmission from wild aquatic birds to poultry. Our results showed that the two strains belong to different groups, one strain (A/mallard/Dalian/DZ-137/2013; abbreviated as DZ137) belongs to Group I, whereas the other strain (A/Eurasian Curlew/Liaoning/ZH-385/2014; abbreviated as ZH385) belongs to Group III. In vitro experiments showed that both DZ137 and ZH385 can replicate efficiently in chicken embryo fibroblast cells. We found that these H13 AIVs can also efficiently replicate in mammalian cell lines, including human embryonic kidney cells and Madin-Darby canine kidney cells. In vivo experiments showed that DZ137 and ZH385 can infect 1-day-old specific pathogen-free (SPF) chickens, and that ZH385 has a higher replication ability in chickens than DZ137. Notably, only ZH385 can replicate efficiently in 10-day-old SPF chickens. However, neither DZ137 nor ZH385 can replicate well in turkeys and quails. Both DZ137 and ZH385 can replicate in 3-week-old mice. Serological surveillance of poultry showed a 4.6%-10.4% (15/328-34/328) antibody-positive rate against H13 AIVs in farm chickens. Our findings indicate that H13 AIVs have the replication ability in chickens and mice and may have a risk of crossing the host barrier from wild aquatic birds to poultry or mammals in the future. |
| format | Article |
| id | doaj-art-211ffdda4bfd43bba56c2ac4cfcd4e6a |
| institution | OA Journals |
| issn | 2222-1751 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Emerging Microbes and Infections |
| spelling | doaj-art-211ffdda4bfd43bba56c2ac4cfcd4e6a2025-08-20T02:30:45ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512023-12-0112110.1080/22221751.2023.2184177Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammalsWeiyang Sun0Menglin Zhao1Zhijun Yu2Yuanguo Li3Xinghai Zhang4Na Feng5Tiecheng Wang6Hongmei Wang7Hongbin He8Yongkun Zhao9Songtao Yang10Xianzhu Xia11Yuwei Gao12Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaPoultry Institute, Shandong Academy of Agricultural Sciences, Ji’nan, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Animal Resistant Biology of Shandong, Ruminant Disease Research Center, College of Life Science, Shandong Normal University, Ji’nan, People’s Republic of ChinaKey Laboratory of Animal Resistant Biology of Shandong, Ruminant Disease Research Center, College of Life Science, Shandong Normal University, Ji’nan, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaKey Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Chang’chun, People’s Republic of ChinaWild aquatic birds are the primary hosts of H13 avian influenza viruses (AIVs). Herein, we performed a genetic analysis of two H13 AIVs isolated from wild birds in China and evaluated their infection potential in poultry to further explore the potential for transmission from wild aquatic birds to poultry. Our results showed that the two strains belong to different groups, one strain (A/mallard/Dalian/DZ-137/2013; abbreviated as DZ137) belongs to Group I, whereas the other strain (A/Eurasian Curlew/Liaoning/ZH-385/2014; abbreviated as ZH385) belongs to Group III. In vitro experiments showed that both DZ137 and ZH385 can replicate efficiently in chicken embryo fibroblast cells. We found that these H13 AIVs can also efficiently replicate in mammalian cell lines, including human embryonic kidney cells and Madin-Darby canine kidney cells. In vivo experiments showed that DZ137 and ZH385 can infect 1-day-old specific pathogen-free (SPF) chickens, and that ZH385 has a higher replication ability in chickens than DZ137. Notably, only ZH385 can replicate efficiently in 10-day-old SPF chickens. However, neither DZ137 nor ZH385 can replicate well in turkeys and quails. Both DZ137 and ZH385 can replicate in 3-week-old mice. Serological surveillance of poultry showed a 4.6%-10.4% (15/328-34/328) antibody-positive rate against H13 AIVs in farm chickens. Our findings indicate that H13 AIVs have the replication ability in chickens and mice and may have a risk of crossing the host barrier from wild aquatic birds to poultry or mammals in the future.https://www.tandfonline.com/doi/10.1080/22221751.2023.2184177Avian influenza virusH13wild aquatic birdspoultrymice |
| spellingShingle | Weiyang Sun Menglin Zhao Zhijun Yu Yuanguo Li Xinghai Zhang Na Feng Tiecheng Wang Hongmei Wang Hongbin He Yongkun Zhao Songtao Yang Xianzhu Xia Yuwei Gao Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals Emerging Microbes and Infections Avian influenza virus H13 wild aquatic birds poultry mice |
| title | Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals |
| title_full | Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals |
| title_fullStr | Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals |
| title_full_unstemmed | Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals |
| title_short | Cross-species infection potential of avian influenza H13 viruses isolated from wild aquatic birds to poultry and mammals |
| title_sort | cross species infection potential of avian influenza h13 viruses isolated from wild aquatic birds to poultry and mammals |
| topic | Avian influenza virus H13 wild aquatic birds poultry mice |
| url | https://www.tandfonline.com/doi/10.1080/22221751.2023.2184177 |
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