Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome

Since the end of 2019, the world has been gripped by a pandemic of a new coronavirus infection caused by SARS-CoV-2. From the first days, the international medical community has been actively studying the acute phase of this infection, but gradually the understanding has come that the number of peop...

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Main Authors: A. A. Starichkova, O. V. Tsygankova, L. D. Khidirova, А. A. Starichkov, P. I. Litvinenko
Format: Article
Language:Russian
Published: Open Systems Publication 2022-03-01
Series:Лечащий Врач
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Online Access:https://journal.lvrach.ru/jour/article/view/897
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author A. A. Starichkova
O. V. Tsygankova
L. D. Khidirova
А. A. Starichkov
P. I. Litvinenko
author_facet A. A. Starichkova
O. V. Tsygankova
L. D. Khidirova
А. A. Starichkov
P. I. Litvinenko
author_sort A. A. Starichkova
collection DOAJ
description Since the end of 2019, the world has been gripped by a pandemic of a new coronavirus infection caused by SARS-CoV-2. From the first days, the international medical community has been actively studying the acute phase of this infection, but gradually the understanding has come that the number of people with long-term consequences, which can be of the most diverse, including multisystem nature, is increasing more and more. The review of the literature reflects current ideas about the short-term and long-term impact of infection with the SARS-CoV-2 virus on the development of electrolyte disorders and the course of cardiovascular pathology, including those that developed de novo. The debatable issues of definition, risk factors, pathogenesis, course of post-COVID syndrome are discussed with the introduction of the official term «states after COVID-19» and its interpretation, according to the World Health Organization definition proposed in the fall of 2021. Separately, the problems of cardiac arrhythmias are highlighted with an emphasis on atrial fibrillation and chronic heart failure, primarily diagnostic ones associated with non-specific dyspnea in such patients and a frequent increase in natriuretic peptides due to non-cardiac causes. It should be emphasized that information on the clinical outcomes, prognosis and pathogenesis of atrial fibrillation in COVID-19 remains controversial, which is due, on the one hand, to the influence of viremia, intoxication, and fever as obvious transient causes of this arrhythmia, and, on the other hand, to the longitudinal prothrombotic status characteristic of SARS-CoV-2 infection. It is known that the largest number of hospitalizations and deaths in the world associated with a new coronavirus infection occurs in elderly and senile people. The atypicality of the clinical picture, polymorbidity, polypharmacy, the presence of geriatric syndromes occupies a special place in the supervision of the gerontological contingent of patients, to which the authors of the review also draw the attention of clinicians.
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institution Kabale University
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series Лечащий Врач
spelling doaj-art-211fc074cc494977bd3fee28cf976f6d2025-08-20T03:57:51ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812022-03-0103495810.51793/OS.2022.25.3.008892Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndromeA. A. Starichkova0O. V. Tsygankova1L. D. Khidirova2А. A. Starichkov3P. I. Litvinenko4Federal State Budgetary Educational Institution of Higher Education Novosibirsk State Medical University of the Ministry of Health of the Russian Federation; State Budgetary Healthcare Institution of the Novosibirsk Region Novosibirsk Regional Hospital No. 2 for War VeteransFederal State Budgetary Educational Institution of Higher Education Novosibirsk State Medical University of the Ministry of Health of the Russian Federation; Research Institute of Therapy and Preventive Medicine – branch of the Federal State Budgetary Scientific Institution Federal Research Center Institute of Cytology and Genetics of the Siberian Branch of the Russian Academy of SciencesFederal State Budgetary Educational Institution of Higher Education Novosibirsk State Medical University of the Ministry of Health of the Russian FederationFederal State Budgetary Educational Institution of Higher Education Novosibirsk State Medical University of the Ministry of Health of the Russian FederationPrivate healthcare institution Clinical Hospital RZD-Medicine NovosibirskSince the end of 2019, the world has been gripped by a pandemic of a new coronavirus infection caused by SARS-CoV-2. From the first days, the international medical community has been actively studying the acute phase of this infection, but gradually the understanding has come that the number of people with long-term consequences, which can be of the most diverse, including multisystem nature, is increasing more and more. The review of the literature reflects current ideas about the short-term and long-term impact of infection with the SARS-CoV-2 virus on the development of electrolyte disorders and the course of cardiovascular pathology, including those that developed de novo. The debatable issues of definition, risk factors, pathogenesis, course of post-COVID syndrome are discussed with the introduction of the official term «states after COVID-19» and its interpretation, according to the World Health Organization definition proposed in the fall of 2021. Separately, the problems of cardiac arrhythmias are highlighted with an emphasis on atrial fibrillation and chronic heart failure, primarily diagnostic ones associated with non-specific dyspnea in such patients and a frequent increase in natriuretic peptides due to non-cardiac causes. It should be emphasized that information on the clinical outcomes, prognosis and pathogenesis of atrial fibrillation in COVID-19 remains controversial, which is due, on the one hand, to the influence of viremia, intoxication, and fever as obvious transient causes of this arrhythmia, and, on the other hand, to the longitudinal prothrombotic status characteristic of SARS-CoV-2 infection. It is known that the largest number of hospitalizations and deaths in the world associated with a new coronavirus infection occurs in elderly and senile people. The atypicality of the clinical picture, polymorbidity, polypharmacy, the presence of geriatric syndromes occupies a special place in the supervision of the gerontological contingent of patients, to which the authors of the review also draw the attention of clinicians.https://journal.lvrach.ru/jour/article/view/897covid-19sars-cov-2new coronavirus infectionlong covidpost covid-19 conditionelderly and senile ageatrial fibrillationheart failurehypоkalemia
spellingShingle A. A. Starichkova
O. V. Tsygankova
L. D. Khidirova
А. A. Starichkov
P. I. Litvinenko
Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
Лечащий Врач
covid-19
sars-cov-2
new coronavirus infection
long covid
post covid-19 condition
elderly and senile age
atrial fibrillation
heart failure
hypоkalemia
title Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
title_full Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
title_fullStr Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
title_full_unstemmed Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
title_short Cardiometabolic disorders in <i>SARS-CoV-2</i> infection and post-covid syndrome
title_sort cardiometabolic disorders in i sars cov 2 i infection and post covid syndrome
topic covid-19
sars-cov-2
new coronavirus infection
long covid
post covid-19 condition
elderly and senile age
atrial fibrillation
heart failure
hypоkalemia
url https://journal.lvrach.ru/jour/article/view/897
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AT aastarichkov cardiometabolicdisordersinisarscov2iinfectionandpostcovidsyndrome
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