Examining the effect of intermittent cycling throughout a 3-h period on peripheral blood concentrations of haemopoietic stem and progenitor cells and cytolytic natural killer cells

Examining the effect of intermittent cycling throughout a 3-h period on peripheral blood concentrations of haemopoietic stem and progenitor cells and cytolytic natural killer cells

Abstract Background Peripheral blood stem cell (PBSC) donation is the primary procedure used to collect haemopoietic stem and progenitor cells (HSPCs) for haemopoietic stem cell transplants (HSCT), however there is a clinical need to reduce collection times and achieve sufficient HSPC doses for succ...

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Bibliographic Details
Main Authors: Phoebe A. Cox, Fendi Pradana, Ella Noble, Samuel J. E. Lucas, Guy Pratt, Mark T. Drayson, Kevin Amin, Francesca A. M. Kinsella, Alex J. Wadley
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Stem Cell Research & Therapy
Subjects:
HSPC
Peripheral blood stem cell donation
Exercise
Interval cycling
Natural killer cell
Transplantation
Online Access:https://doi.org/10.1186/s13287-025-04261-1
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