Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease
Abstract Background With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population of head and neck cancer survivors that are different from preceding decades. In addition, thei...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-07-01
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| Series: | Journal of Otolaryngology - Head and Neck Surgery |
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| Online Access: | http://link.springer.com/article/10.1186/s40463-020-00443-4 |
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| author | Jin Soo Song Patrick Vallance Vincent Biron Caroline C. Jeffery |
| author_facet | Jin Soo Song Patrick Vallance Vincent Biron Caroline C. Jeffery |
| author_sort | Jin Soo Song |
| collection | DOAJ |
| description | Abstract Background With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population of head and neck cancer survivors that are different from preceding decades. In addition, their long-term survivorship issues have become increasing research interests. This study was undertaken to determine the changing epidemiological trends of head and neck cancer survivors in Alberta to better anticipate future demands on healthcare services. Methods The Alberta Cancer Registry was queried for adult (aged > 18 years), head and neck cancer (HNC) patients who were at least 1-year post-treatment completion between 1997 to 2016. Cutaneous head and neck and thyroid cancer patients were excluded. Extracted data was then used to calculate the incidence and prevalence of early (< 5 years from treatment), intermediate (5 to < 10 years from treatment), and late (> 10 years from treatment) survivors of head and neck cancer. Point prevalence of HNC survivors in 2005, 2010, and 2015 were then further stratified by gender, sub-site and age. Results Over this time period, head and neck cancer survivors tended to be younger (64.0 vs. 62.1, p = 0.046) and male (M:F 2.45:1 vs 2.54:1). In 1997, the predominant subsites were the oral cavity and larynx at 45.8% and 30.9%, respectively. In 2015 the predominant subsites were the oral cavity and oropharynx at 33.0% and 29.4%, respectively. Within the cohort, the prevalence of late HNC survivors increased to 13.3 per 100,000 people in 2015. Conclusions There is a significant population of head and neck survivors who are younger, male, and more than 10 years post-treatment. While oral cavity cancers have shown stable disease prevalence in recent decades, the number of OPSCC survivors have increased. With an improved understanding of the distribution and characteristics of HNC survivors, a more guided healthcare support network can be fostered for these patients. |
| format | Article |
| id | doaj-art-210a3f08345f4c48b19eaadb691c64f7 |
| institution | Kabale University |
| issn | 1916-0216 |
| language | English |
| publishDate | 2020-07-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of Otolaryngology - Head and Neck Surgery |
| spelling | doaj-art-210a3f08345f4c48b19eaadb691c64f72025-02-03T00:22:58ZengSAGE PublishingJournal of Otolaryngology - Head and Neck Surgery1916-02162020-07-014911610.1186/s40463-020-00443-4Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of diseaseJin Soo Song0Patrick Vallance1Vincent Biron2Caroline C. Jeffery3Faculty of Medicine and Dentistry, University of AlbertaFaculty of Medicine and Dentistry, University of AlbertaFaculty of Medicine and Dentistry, University of AlbertaFaculty of Medicine and Dentistry, University of AlbertaAbstract Background With an increase in the incidence of human papillomavirus (HPV)-associated oropharyngeal squamous cell carcinoma (OPSCC) and more favourable survival outcomes, there is now a population of head and neck cancer survivors that are different from preceding decades. In addition, their long-term survivorship issues have become increasing research interests. This study was undertaken to determine the changing epidemiological trends of head and neck cancer survivors in Alberta to better anticipate future demands on healthcare services. Methods The Alberta Cancer Registry was queried for adult (aged > 18 years), head and neck cancer (HNC) patients who were at least 1-year post-treatment completion between 1997 to 2016. Cutaneous head and neck and thyroid cancer patients were excluded. Extracted data was then used to calculate the incidence and prevalence of early (< 5 years from treatment), intermediate (5 to < 10 years from treatment), and late (> 10 years from treatment) survivors of head and neck cancer. Point prevalence of HNC survivors in 2005, 2010, and 2015 were then further stratified by gender, sub-site and age. Results Over this time period, head and neck cancer survivors tended to be younger (64.0 vs. 62.1, p = 0.046) and male (M:F 2.45:1 vs 2.54:1). In 1997, the predominant subsites were the oral cavity and larynx at 45.8% and 30.9%, respectively. In 2015 the predominant subsites were the oral cavity and oropharynx at 33.0% and 29.4%, respectively. Within the cohort, the prevalence of late HNC survivors increased to 13.3 per 100,000 people in 2015. Conclusions There is a significant population of head and neck survivors who are younger, male, and more than 10 years post-treatment. While oral cavity cancers have shown stable disease prevalence in recent decades, the number of OPSCC survivors have increased. With an improved understanding of the distribution and characteristics of HNC survivors, a more guided healthcare support network can be fostered for these patients.http://link.springer.com/article/10.1186/s40463-020-00443-4DemographicsEpidemiologyHead and neck CancerSurvivorsSurvivorshipCanada |
| spellingShingle | Jin Soo Song Patrick Vallance Vincent Biron Caroline C. Jeffery Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease Journal of Otolaryngology - Head and Neck Surgery Demographics Epidemiology Head and neck Cancer Survivors Survivorship Canada |
| title | Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease |
| title_full | Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease |
| title_fullStr | Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease |
| title_full_unstemmed | Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease |
| title_short | Epidemiological trends of head and neck Cancer survivors in Alberta: towards improved understanding of the burden of disease |
| title_sort | epidemiological trends of head and neck cancer survivors in alberta towards improved understanding of the burden of disease |
| topic | Demographics Epidemiology Head and neck Cancer Survivors Survivorship Canada |
| url | http://link.springer.com/article/10.1186/s40463-020-00443-4 |
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