A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images

Texture features related to scar collagen second harmonic generation (SHG) images are useful for studying scars; however, current computational analysis methods require extensive computing resources. We designed a local orientation ternary pattern (LOTP) method in the SHG images for the purpose of e...

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Main Authors: Guannan Chen, Gaoqiang Liu, Xiaoqin Zhu, Mingyu Liu, Encai Zhang, Jichun Li, Kun Zhang, Lihang Lin
Format: Article
Language:English
Published: IEEE 2017-01-01
Series:IEEE Photonics Journal
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Online Access:https://ieeexplore.ieee.org/document/7873335/
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author Guannan Chen
Gaoqiang Liu
Xiaoqin Zhu
Mingyu Liu
Encai Zhang
Jichun Li
Kun Zhang
Lihang Lin
author_facet Guannan Chen
Gaoqiang Liu
Xiaoqin Zhu
Mingyu Liu
Encai Zhang
Jichun Li
Kun Zhang
Lihang Lin
author_sort Guannan Chen
collection DOAJ
description Texture features related to scar collagen second harmonic generation (SHG) images are useful for studying scars; however, current computational analysis methods require extensive computing resources. We designed a local orientation ternary pattern (LOTP) method in the SHG images for the purpose of extracting the characterization. SHG images were generated from human scar tissue samples, with scar age ranging from 2 to 40 years. Depending on the complete texture information of LOTP images, we extracted the Tamura features including coarseness, contrast, directionality, regularity, line-likeness, and roughness. Tamura texture features could be measured for all input patterns to set up a regression model about the age of scars and that give well-distributed results. Generalized boosted regression trees were calculated with the computed data, and R<sup>2</sup> and root-mean-square error (RMSE) statistical analysis were used to determine accuracy. Use of the LOTP operator allowed for the maximum extraction and relative importance of Tamura feature data, with roughness being the most important feature and line-likeness being the least important feature. Using the LOTP operator resulted in the highest accuracy assessment of scar characteristics compared to other methods, such as improving local ternary pattern, binary gradient contours, and grey level co-occurrence. Our proposed LOTP method requires less computation time than the extension of LTP and describes SHG images with higher accuracy compared to existing algorithms.
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spelling doaj-art-20f3845d4abc46e5821aaa37bee533c12025-08-20T03:32:37ZengIEEEIEEE Photonics Journal1943-06552017-01-019211310.1109/JPHOT.2017.26791047873335A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation ImagesGuannan Chen0Gaoqiang Liu1Xiaoqin Zhu2Mingyu Liu3Encai Zhang4Jichun Li5Kun Zhang6Lihang Lin7Institute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaInstitute of Laser and Optoelectronics Technology, Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of Opto-Electronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, ChinaDepartment of Dermatology, Affiliated Union Hospital Fujian Medical University, Fuzhou, ChinaTexture features related to scar collagen second harmonic generation (SHG) images are useful for studying scars; however, current computational analysis methods require extensive computing resources. We designed a local orientation ternary pattern (LOTP) method in the SHG images for the purpose of extracting the characterization. SHG images were generated from human scar tissue samples, with scar age ranging from 2 to 40 years. Depending on the complete texture information of LOTP images, we extracted the Tamura features including coarseness, contrast, directionality, regularity, line-likeness, and roughness. Tamura texture features could be measured for all input patterns to set up a regression model about the age of scars and that give well-distributed results. Generalized boosted regression trees were calculated with the computed data, and R<sup>2</sup> and root-mean-square error (RMSE) statistical analysis were used to determine accuracy. Use of the LOTP operator allowed for the maximum extraction and relative importance of Tamura feature data, with roughness being the most important feature and line-likeness being the least important feature. Using the LOTP operator resulted in the highest accuracy assessment of scar characteristics compared to other methods, such as improving local ternary pattern, binary gradient contours, and grey level co-occurrence. Our proposed LOTP method requires less computation time than the extension of LTP and describes SHG images with higher accuracy compared to existing algorithms.https://ieeexplore.ieee.org/document/7873335/Generalized boosted regression trees (GBRT)local orientation ternary pattern (LOTP)second harmonic generation (SHG) imageTamura texture features.
spellingShingle Guannan Chen
Gaoqiang Liu
Xiaoqin Zhu
Mingyu Liu
Encai Zhang
Jichun Li
Kun Zhang
Lihang Lin
A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
IEEE Photonics Journal
Generalized boosted regression trees (GBRT)
local orientation ternary pattern (LOTP)
second harmonic generation (SHG) image
Tamura texture features.
title A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
title_full A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
title_fullStr A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
title_full_unstemmed A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
title_short A Novel Method for Describing Texture of Scar Collagen Using Second Harmonic Generation Images
title_sort novel method for describing texture of scar collagen using second harmonic generation images
topic Generalized boosted regression trees (GBRT)
local orientation ternary pattern (LOTP)
second harmonic generation (SHG) image
Tamura texture features.
url https://ieeexplore.ieee.org/document/7873335/
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