Development of a whole-exome sequencing kit to facilitate porcine biomedical research

Development of a whole-exome sequencing kit to facilitate porcine biomedical research

Abstract Background It is important for porcine models to replicate gene mutations present in human diseases to improve the translatability of animal studies. In this study, the high efficacy of a whole exome sequencing kit was demonstrated for the improved pig reference genome (Sus scrofa 11.1) to...

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Bibliographic Details
Main Authors: Vishwaarth Vijayakumar, Tanvi Joshi, Lobna Elkhadragy, Lawrence B. Schook, Ron C. Gaba, Mohammed El-Kebir, Kyle M. Schachtschneider
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Genome Biology
Subjects:
Porcine animal models
Single nucleotide variants
Liver cancer
Exome sequencing
Online Access:https://doi.org/10.1186/s13059-025-03589-4
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