Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System
Nicholas R Binder,1 Jeffrey M Bloom,1 Mineh Balushian Haftevani,1 Stephen Duncan,1 Nathan Christopher Lowry,2 Tom S Chang1 1Vitreoretinal Surgery, Acuity Eye Group, Los Angeles, CA, USA; 2Intelligent DX, Los Angeles, CA, USACorrespondence: Jeffrey M Bloom, Acuity Eye Group, 288 N Santa Anita Ave, Su...
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Dove Medical Press
2024-12-01
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| Series: | Clinical Ophthalmology |
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| author | Binder NR Bloom JM Balushian Haftevani M Duncan S Lowry NC Chang TS |
| author_facet | Binder NR Bloom JM Balushian Haftevani M Duncan S Lowry NC Chang TS |
| author_sort | Binder NR |
| collection | DOAJ |
| description | Nicholas R Binder,1 Jeffrey M Bloom,1 Mineh Balushian Haftevani,1 Stephen Duncan,1 Nathan Christopher Lowry,2 Tom S Chang1 1Vitreoretinal Surgery, Acuity Eye Group, Los Angeles, CA, USA; 2Intelligent DX, Los Angeles, CA, USACorrespondence: Jeffrey M Bloom, Acuity Eye Group, 288 N Santa Anita Ave, Suite 403, Arcadia, CA, 91006, USA, Email Jmbloom92@gmail.comPurpose: Our aim is to evaluate the sensitivity and specificity of Acuity 360 telemedicine system, as compared to in-person clinic examination, in identifying clinically significant eye disease. Acuity 360 is a combination of commercially available ocular imaging devices used together to provide a comprehensive evaluation of the structures and diseases of the eye.Methods: Observational cross-sectional study of consecutively examined patients where 19 remote examiners analyzed 80 patients using Acuity 360 images. The examiners’ diagnoses were compared to the diagnosis obtained from in-person clinic examination of all the patients. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), false-negative rate, and inter-rater agreement were calculated.Results: Compared to in-person clinic examination, the sensitivity, specificity, PPV, NPV, and false-negative rate for the optical coherence tomography (OCT) of optic nerve were 95.8%, 98.5%, 86.8%, 99.6%, 0.39% and for the combined retina examination (OCT of the macula and widefield fundus photography) were 93.4%, 88.5%, 80.2%, 96.4%, 2.19%, respectively. The median inter-rater agreement the OCT of optic nerve and the combined retina examination were each 95%.Conclusion: The Acuity 360 telemedicine system has a low false-negative rate and is highly sensitive and specific when compared to an in-person clinic examination. It can determine the necessity for specialist referral and triage the patients that require urgent treatment. High inter-rater agreement shows that it is effective with minimal variability in analyzing the Acuity 360 images by remote examiners.Keywords: tele-ophthalmology, telemedicine, sensitivity, specificity, optical coherence tomography |
| format | Article |
| id | doaj-art-20e84f1d16c04199a9d90f54e07bb026 |
| institution | Kabale University |
| issn | 1177-5483 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Clinical Ophthalmology |
| spelling | doaj-art-20e84f1d16c04199a9d90f54e07bb0262024-12-19T17:40:22ZengDove Medical PressClinical Ophthalmology1177-54832024-12-01Volume 183853385998530Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening SystemBinder NRBloom JMBalushian Haftevani MDuncan SLowry NCChang TSNicholas R Binder,1 Jeffrey M Bloom,1 Mineh Balushian Haftevani,1 Stephen Duncan,1 Nathan Christopher Lowry,2 Tom S Chang1 1Vitreoretinal Surgery, Acuity Eye Group, Los Angeles, CA, USA; 2Intelligent DX, Los Angeles, CA, USACorrespondence: Jeffrey M Bloom, Acuity Eye Group, 288 N Santa Anita Ave, Suite 403, Arcadia, CA, 91006, USA, Email Jmbloom92@gmail.comPurpose: Our aim is to evaluate the sensitivity and specificity of Acuity 360 telemedicine system, as compared to in-person clinic examination, in identifying clinically significant eye disease. Acuity 360 is a combination of commercially available ocular imaging devices used together to provide a comprehensive evaluation of the structures and diseases of the eye.Methods: Observational cross-sectional study of consecutively examined patients where 19 remote examiners analyzed 80 patients using Acuity 360 images. The examiners’ diagnoses were compared to the diagnosis obtained from in-person clinic examination of all the patients. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), false-negative rate, and inter-rater agreement were calculated.Results: Compared to in-person clinic examination, the sensitivity, specificity, PPV, NPV, and false-negative rate for the optical coherence tomography (OCT) of optic nerve were 95.8%, 98.5%, 86.8%, 99.6%, 0.39% and for the combined retina examination (OCT of the macula and widefield fundus photography) were 93.4%, 88.5%, 80.2%, 96.4%, 2.19%, respectively. The median inter-rater agreement the OCT of optic nerve and the combined retina examination were each 95%.Conclusion: The Acuity 360 telemedicine system has a low false-negative rate and is highly sensitive and specific when compared to an in-person clinic examination. It can determine the necessity for specialist referral and triage the patients that require urgent treatment. High inter-rater agreement shows that it is effective with minimal variability in analyzing the Acuity 360 images by remote examiners.Keywords: tele-ophthalmology, telemedicine, sensitivity, specificity, optical coherence tomographyhttps://www.dovepress.com/evaluation-of-sensitivity-and-specificity-of-acuity-360-telemedicine-v-peer-reviewed-fulltext-article-OPTHtele-ophthalmologytelemedicinesensitivityspecificityoptical coherence tomography |
| spellingShingle | Binder NR Bloom JM Balushian Haftevani M Duncan S Lowry NC Chang TS Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System Clinical Ophthalmology tele-ophthalmology telemedicine sensitivity specificity optical coherence tomography |
| title | Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System |
| title_full | Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System |
| title_fullStr | Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System |
| title_full_unstemmed | Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System |
| title_short | Evaluation of Sensitivity and Specificity of Acuity 360 Telemedicine Vision Screening System |
| title_sort | evaluation of sensitivity and specificity of acuity 360 telemedicine vision screening system |
| topic | tele-ophthalmology telemedicine sensitivity specificity optical coherence tomography |
| url | https://www.dovepress.com/evaluation-of-sensitivity-and-specificity-of-acuity-360-telemedicine-v-peer-reviewed-fulltext-article-OPTH |
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