Changes in insulin, adiponectin and lipid concentrations with age are associated with frailty and reduced quality of life in dogs

Changes in insulin, adiponectin and lipid concentrations with age are associated with frailty and reduced quality of life in dogs

Abstract Declining metabolic function with aging is a conserved phenotype across many species. While aging-associated changes in metabolic status have been investigated rigorously in humans, less is known about metabolic aging in dogs. In this cross-sectional study, we aimed to examine changes in me...

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Main Authors: Brennen McKenzie, Matthew Peloquin, Jessica L. Graves, Frances Chen, Ashley Tovar, Tennery A. Carttar, Katya Tucker, Kenny Vo, Michelle Nelson, Kaitlyn M. Super, Jessica Austriaco, Sunny Y. Weber, Alexander Naka, Erin E. McCandless, Karen Greenwood, Dina Juarez-Salinas, Celine-Lea Halioua-Haubold, Ellen R. Ratcliff
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-89923-z
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