Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds
The antimicrobial and tyrosinase enzyme inhibition activities of various extracts and isolated compounds of Limonium meyeri were investigated. Apigenin-7-O-β-glucuronide and myricetin 3-O-α-rhamnoside were isolated from the ethyl acetate fraction using chromatographic methods. Methanol extract showe...
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North Carolina State University
2025-01-01
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| Series: | BioResources |
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| Online Access: | https://ojs.bioresources.com/index.php/BRJ/article/view/24083 |
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| author | Masum Sami Esen Sezen Karaoğlan Hayrunisa Hancı Cavit Kazaz |
| author_facet | Masum Sami Esen Sezen Karaoğlan Hayrunisa Hancı Cavit Kazaz |
| author_sort | Masum Sami |
| collection | DOAJ |
| description | The antimicrobial and tyrosinase enzyme inhibition activities of various extracts and isolated compounds of Limonium meyeri were investigated. Apigenin-7-O-β-glucuronide and myricetin 3-O-α-rhamnoside were isolated from the ethyl acetate fraction using chromatographic methods. Methanol extract showed 62.0% and ethyl acetate extract showed 57.6% tyrosinase enzyme inhibition activities at 400 µg/mL concentration. Myricetin 3-O-α-rhamnoside (IC50 = 27.7 ± 0.6 µg/mL) showed higher tyrosinase enzyme inhibitory effect than apigenin-7-O-β-glucuronide (IC50 = 43.0 ± 0.9 µg/mL). n-Hexane extract was found to be effective against Enterococcus faecalis (MIC = 1 µg/mL), while methanol extract was effective against Pseudomonas aeruginosa (MIC = 16 µg/mL). Myricetin 3-O-α-rhamnoside showed antimicrobial effect against Enterococcus faecalis (MIC = 128 µg/mL). Thus, Limonium meyeri and its compounds may provide valuable insights for future studies as antityrosinase and antibacterial agents. |
| format | Article |
| id | doaj-art-20bb755b237347ea8ad2e3649d5dbf84 |
| institution | Kabale University |
| issn | 1930-2126 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | North Carolina State University |
| record_format | Article |
| series | BioResources |
| spelling | doaj-art-20bb755b237347ea8ad2e3649d5dbf842025-02-10T23:56:27ZengNorth Carolina State UniversityBioResources1930-21262025-01-01201217121822316Some Bioactivities of Limonium meyeri Extracts and their Separated CompoundsMasum Sami0Esen Sezen Karaoğlan1https://orcid.org/0000-0002-9098-9021Hayrunisa Hancı2https://orcid.org/0000-0002-3644-8531Cavit Kazaz3https://orcid.org/0000-0002-5249-0895Ataturk University, Faculty of Pharmacy, Department of Pharmacognosy, Erzurum, TurkeyAtaturk University, Faculty of Pharmacy, Department of Pharmaceutical Botany, Erzurum, TurkeyAtaturk University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Erzurum, TurkeyAtaturk University, Faculty of Science, Department of Chemistry, Erzurum, TurkeyThe antimicrobial and tyrosinase enzyme inhibition activities of various extracts and isolated compounds of Limonium meyeri were investigated. Apigenin-7-O-β-glucuronide and myricetin 3-O-α-rhamnoside were isolated from the ethyl acetate fraction using chromatographic methods. Methanol extract showed 62.0% and ethyl acetate extract showed 57.6% tyrosinase enzyme inhibition activities at 400 µg/mL concentration. Myricetin 3-O-α-rhamnoside (IC50 = 27.7 ± 0.6 µg/mL) showed higher tyrosinase enzyme inhibitory effect than apigenin-7-O-β-glucuronide (IC50 = 43.0 ± 0.9 µg/mL). n-Hexane extract was found to be effective against Enterococcus faecalis (MIC = 1 µg/mL), while methanol extract was effective against Pseudomonas aeruginosa (MIC = 16 µg/mL). Myricetin 3-O-α-rhamnoside showed antimicrobial effect against Enterococcus faecalis (MIC = 128 µg/mL). Thus, Limonium meyeri and its compounds may provide valuable insights for future studies as antityrosinase and antibacterial agents.https://ojs.bioresources.com/index.php/BRJ/article/view/24083limonium meyeriapigenin-7-o-β-glucuronidemyricetin 3-o-α-rhamnosideantimicrobialantityrosinase |
| spellingShingle | Masum Sami Esen Sezen Karaoğlan Hayrunisa Hancı Cavit Kazaz Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds BioResources limonium meyeri apigenin-7-o-β-glucuronide myricetin 3-o-α-rhamnoside antimicrobial antityrosinase |
| title | Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds |
| title_full | Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds |
| title_fullStr | Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds |
| title_full_unstemmed | Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds |
| title_short | Some Bioactivities of Limonium meyeri Extracts and their Separated Compounds |
| title_sort | some bioactivities of limonium meyeri extracts and their separated compounds |
| topic | limonium meyeri apigenin-7-o-β-glucuronide myricetin 3-o-α-rhamnoside antimicrobial antityrosinase |
| url | https://ojs.bioresources.com/index.php/BRJ/article/view/24083 |
| work_keys_str_mv | AT masumsami somebioactivitiesoflimoniummeyeriextractsandtheirseparatedcompounds AT esensezenkaraoglan somebioactivitiesoflimoniummeyeriextractsandtheirseparatedcompounds AT hayrunisahancı somebioactivitiesoflimoniummeyeriextractsandtheirseparatedcompounds AT cavitkazaz somebioactivitiesoflimoniummeyeriextractsandtheirseparatedcompounds |