Uncovering gene and cellular signatures of immune checkpoint response via machine learning and single-cell RNA-seq
Abstract Immune checkpoint inhibitors have transformed cancer therapy. However, only a fraction of patients benefit from these treatments. The variability in patient responses remains a significant challenge due to the intricate nature of the tumor microenvironment. Here, we harness single-cell RNA-...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-04-01
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| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-00883-z |
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