Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities
SARS-CoV-2, a newly discovered coronavirus, has been linked to the COVID-19 pandemic and is currently an important public health issue. Despite all the work done to date around the world, there is still no viable treatment for COVID-19. This study examined the most recent evidence on the efficacy an...
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| Format: | Article |
| Language: | English |
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Sciendo
2023-06-01
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| Series: | Acta Pharmaceutica |
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| Online Access: | https://doi.org/10.2478/acph-2023-0014 |
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| author | Fan Sijia Wang Hongling Wu Dean Liu Lu |
| author_facet | Fan Sijia Wang Hongling Wu Dean Liu Lu |
| author_sort | Fan Sijia |
| collection | DOAJ |
| description | SARS-CoV-2, a newly discovered coronavirus, has been linked to the COVID-19 pandemic and is currently an important public health issue. Despite all the work done to date around the world, there is still no viable treatment for COVID-19. This study examined the most recent evidence on the efficacy and safety of several therapeutic options available including natural substances, synthetic drugs and vaccines in the treatment of COVID-19. Various natural compounds such as sarsapogenin, lycorine, biscoclaurine, vitamin B12, glycyrrhizic acid, riboflavin, resveratrol and kaempferol, various vaccines and drugs such as AZD1222, mRNA-1273, BNT162b2, Sputnik V, and remdesivir, lopinavir, favipiravir, darunavir, oseltamivir, and umifenovir, resp., have been discussed comprehensively. We attempted to provide exhaustive information regarding the various prospective therapeutic approaches available in order to assist researchers and physicians in treating COVID-19 patients. |
| format | Article |
| id | doaj-art-20a7c636872948e0b043e405a2386947 |
| institution | Kabale University |
| issn | 1846-9558 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Pharmaceutica |
| spelling | doaj-art-20a7c636872948e0b043e405a23869472025-02-02T17:57:33ZengSciendoActa Pharmaceutica1846-95582023-06-0173215717310.2478/acph-2023-0014Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunitiesFan Sijia0Wang Hongling1Wu Dean2Liu Lu31Department of Intensive Care Unit, South China Hospital, Health Science Center Shenzhen University Guangdong, Shenzhen 518116, P. R.China2Department of Cardiothoracic Surgery940th Hospital of Joint Logistic Support Force of PLA, Lanzhou, Gansu, 730050, P. R.China3Department of Respiratory Medicine, The Third People’s Hospital of Gansu Province Lanzhou University, Lanzhou, Gansu 730050, P. R.China4The First Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital of China Medical University, Shenyang Liaoning, 110032, P. R.ChinaSARS-CoV-2, a newly discovered coronavirus, has been linked to the COVID-19 pandemic and is currently an important public health issue. Despite all the work done to date around the world, there is still no viable treatment for COVID-19. This study examined the most recent evidence on the efficacy and safety of several therapeutic options available including natural substances, synthetic drugs and vaccines in the treatment of COVID-19. Various natural compounds such as sarsapogenin, lycorine, biscoclaurine, vitamin B12, glycyrrhizic acid, riboflavin, resveratrol and kaempferol, various vaccines and drugs such as AZD1222, mRNA-1273, BNT162b2, Sputnik V, and remdesivir, lopinavir, favipiravir, darunavir, oseltamivir, and umifenovir, resp., have been discussed comprehensively. We attempted to provide exhaustive information regarding the various prospective therapeutic approaches available in order to assist researchers and physicians in treating COVID-19 patients.https://doi.org/10.2478/acph-2023-0014covid-19sars-cov-2drugsnatural compoundsvaccinetreatment |
| spellingShingle | Fan Sijia Wang Hongling Wu Dean Liu Lu Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities Acta Pharmaceutica covid-19 sars-cov-2 drugs natural compounds vaccine treatment |
| title | Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities |
| title_full | Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities |
| title_fullStr | Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities |
| title_full_unstemmed | Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities |
| title_short | Pharmaceutical approaches for COVID-19: An update on current therapeutic opportunities |
| title_sort | pharmaceutical approaches for covid 19 an update on current therapeutic opportunities |
| topic | covid-19 sars-cov-2 drugs natural compounds vaccine treatment |
| url | https://doi.org/10.2478/acph-2023-0014 |
| work_keys_str_mv | AT fansijia pharmaceuticalapproachesforcovid19anupdateoncurrenttherapeuticopportunities AT wanghongling pharmaceuticalapproachesforcovid19anupdateoncurrenttherapeuticopportunities AT wudean pharmaceuticalapproachesforcovid19anupdateoncurrenttherapeuticopportunities AT liulu pharmaceuticalapproachesforcovid19anupdateoncurrenttherapeuticopportunities |