Neuroprotective effects of Daphnetin on hippocampal neurons and blood-brain barrier integrity in a mouse model of cerebral ischemia

Neuroprotective effects of Daphnetin on hippocampal neurons and blood-brain barrier integrity in a mouse model of cerebral ischemia

The purpose of this research was to assess the impact of different doses of Daphnetin (DAP, a natural compound derived from coumarin) on hippocampus neuronal injury, neurobehavioral function, blood-brain barrier (BBB) integrity, expression of claudin-5, brain-derived neurotrophic factor (BDNF), supe...

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Bibliographic Details
Main Authors: Maysam Havasi Mehr, Shahein Momenabadi, Ali Vakili, Abbas Pakdel, Abbas Ali Vafaei, Abedin Vakili
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Brain Research Bulletin
Subjects:
Daphnetin
Cerebral ischemia
Hippocampus
BBB
Spatial memory
Claudin-5
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923024002375
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