D-mannose suppresses the angiogenesis and progression of colorectal cancer

D-mannose suppresses the angiogenesis and progression of colorectal cancer

Angiogenesis is an important factor influencing the development of solid tumors, and vascular endothelial growth factor receptor-2 (VEGFR2) is a central regulator of angiogenesis. Antibodies and inhibitors against VEGFR2 have been widely used in various malignancies. However, the regulatory mechanis...

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Bibliographic Details
Main Authors: Du Yu, Zhang Xinchao, Xu Yixin, Zhou Yuefan, Xu Yanping
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2025-04-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
D-mannose
VEGFR2
GSK3β
TFE3
CRC
lysosome
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2025043
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