Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort

Background: Brain MRI in infants at ultra-high-field scanners might improve diagnostic quality, but safety should be evaluated first. In our previous study, we reported simulated specific absorption rates and acoustic noise data at 7 Tesla. Methods: In this study, we included twenty infants between...

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Main Authors: I.M. van Ooijen, K.V. Annink, M.J.N.L. Benders, J. Dudink, T. Alderliesten, F. Groenendaal, M.L. Tataranno, M.H. Lequin, J.M. Hoogduin, F. Visser, A.J.E. Raaijmakers, D.W.J. Klomp, E.C. Wiegers, J.P. Wijnen, N.E. van der Aa
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:NeuroImage: Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S266695602300020X
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author I.M. van Ooijen
K.V. Annink
M.J.N.L. Benders
J. Dudink
T. Alderliesten
F. Groenendaal
M.L. Tataranno
M.H. Lequin
J.M. Hoogduin
F. Visser
A.J.E. Raaijmakers
D.W.J. Klomp
E.C. Wiegers
J.P. Wijnen
N.E. van der Aa
author_facet I.M. van Ooijen
K.V. Annink
M.J.N.L. Benders
J. Dudink
T. Alderliesten
F. Groenendaal
M.L. Tataranno
M.H. Lequin
J.M. Hoogduin
F. Visser
A.J.E. Raaijmakers
D.W.J. Klomp
E.C. Wiegers
J.P. Wijnen
N.E. van der Aa
author_sort I.M. van Ooijen
collection DOAJ
description Background: Brain MRI in infants at ultra-high-field scanners might improve diagnostic quality, but safety should be evaluated first. In our previous study, we reported simulated specific absorption rates and acoustic noise data at 7 Tesla. Methods: In this study, we included twenty infants between term-equivalent age and three months of age. The infants were scanned on a 7 Tesla MRI directly after their clinically indicated 3 Tesla brain MRI scan. Vital parameters, temperature, and comfort were monitored throughout the process. Brain temperature was estimated during the MRI scans using proton MR spectroscopy. Results: We found no significant differences in vital parameters, temperature, and comfort during and after 7 Tesla MRI scans, compared to 3 Tesla MRI scans. Conclusions: These data confirm our hypothesis that scanning infants at 7 Tesla MRI appears to be safe and we identified no additional risks from scanning at 3 Tesla MRI.
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spelling doaj-art-208fd7790c6443d3a0ed8560cfd975412025-08-20T01:55:37ZengElsevierNeuroImage: Reports2666-95602023-06-013210017510.1016/j.ynirp.2023.100175Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfortI.M. van Ooijen0K.V. Annink1M.J.N.L. Benders2J. Dudink3T. Alderliesten4F. Groenendaal5M.L. Tataranno6M.H. Lequin7J.M. Hoogduin8F. Visser9A.J.E. Raaijmakers10D.W.J. Klomp11E.C. Wiegers12J.P. Wijnen13N.E. van der Aa14Department of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the Netherlands; Centre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartment of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsDepartement of Radiology, Division of Imaging and Oncology, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the NetherlandsCentre for Image Sciences, High Field MR Research, University Medical Center Utrecht, University Utrecht, Utrecht, the Netherlands; Correspondence author.Department of Neonatology, University Medical Center Utrecht, Utrecht Brain Center, University Utrecht, Utrecht, the NetherlandsBackground: Brain MRI in infants at ultra-high-field scanners might improve diagnostic quality, but safety should be evaluated first. In our previous study, we reported simulated specific absorption rates and acoustic noise data at 7 Tesla. Methods: In this study, we included twenty infants between term-equivalent age and three months of age. The infants were scanned on a 7 Tesla MRI directly after their clinically indicated 3 Tesla brain MRI scan. Vital parameters, temperature, and comfort were monitored throughout the process. Brain temperature was estimated during the MRI scans using proton MR spectroscopy. Results: We found no significant differences in vital parameters, temperature, and comfort during and after 7 Tesla MRI scans, compared to 3 Tesla MRI scans. Conclusions: These data confirm our hypothesis that scanning infants at 7 Tesla MRI appears to be safe and we identified no additional risks from scanning at 3 Tesla MRI.http://www.sciencedirect.com/science/article/pii/S266695602300020XInfantsUltra-high-field (7 Tesla) MRINeuroimagingSafety
spellingShingle I.M. van Ooijen
K.V. Annink
M.J.N.L. Benders
J. Dudink
T. Alderliesten
F. Groenendaal
M.L. Tataranno
M.H. Lequin
J.M. Hoogduin
F. Visser
A.J.E. Raaijmakers
D.W.J. Klomp
E.C. Wiegers
J.P. Wijnen
N.E. van der Aa
Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
NeuroImage: Reports
Infants
Ultra-high-field (7 Tesla) MRI
Neuroimaging
Safety
title Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
title_full Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
title_fullStr Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
title_full_unstemmed Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
title_short Introduction of ultra-high-field MR brain imaging in infants: vital parameters, temperature and comfort
title_sort introduction of ultra high field mr brain imaging in infants vital parameters temperature and comfort
topic Infants
Ultra-high-field (7 Tesla) MRI
Neuroimaging
Safety
url http://www.sciencedirect.com/science/article/pii/S266695602300020X
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