New perspectives on probiotics in health and disease
The gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90% bacteria. Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel disea...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2015-06-01
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| Series: | Food Science and Human Wellness |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2213453015000300 |
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| author | Eric Banan-Mwine Daliri Byong H. Lee |
| author_facet | Eric Banan-Mwine Daliri Byong H. Lee |
| author_sort | Eric Banan-Mwine Daliri |
| collection | DOAJ |
| description | The gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90% bacteria. Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel diseases, obesity, oral health, etc. have been proposed. What is the real role of probiotics, prebiotics and synbiotics in influencing a healthy microbiota? Both in vitro evidences and in vivo clinical data have supported some of these new health claims, while recent molecular advancement has provided strong indications to support and justify the hypotheses. However, probiotics validity and health claims have continuously been rejected on the basis of “biomarker deficiency”. To battle the increase in health care costs, a preventive approach to medicine with the development of probiotics and prebiotics or symbiotic products is being advanced. This review discusses the potential beneficial effects of probiotics in preventing and treating certain diseases as well as current and future perspectives of probiotic research. |
| format | Article |
| id | doaj-art-2080bc32c6e7498582e3dd9b597893d9 |
| institution | Kabale University |
| issn | 2213-4530 |
| language | English |
| publishDate | 2015-06-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-2080bc32c6e7498582e3dd9b597893d92025-02-03T06:52:27ZengTsinghua University PressFood Science and Human Wellness2213-45302015-06-0142566510.1016/j.fshw.2015.06.002New perspectives on probiotics in health and diseaseEric Banan-Mwine Daliri0Byong H. Lee1School of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, ChinaSchool of Biotechnology, Jiangnan University, 1800 Lihu Avenue, Wuxi 214122, ChinaThe gut microbiota continues to fascinate scientists in many realms when it is considered that humans contain 90% bacteria. Correlations between changes in composition and activity of the gut microbiota and common disorders such as cancer, hypertension, hypercholesterolemia, inflammatory bowel diseases, obesity, oral health, etc. have been proposed. What is the real role of probiotics, prebiotics and synbiotics in influencing a healthy microbiota? Both in vitro evidences and in vivo clinical data have supported some of these new health claims, while recent molecular advancement has provided strong indications to support and justify the hypotheses. However, probiotics validity and health claims have continuously been rejected on the basis of “biomarker deficiency”. To battle the increase in health care costs, a preventive approach to medicine with the development of probiotics and prebiotics or symbiotic products is being advanced. This review discusses the potential beneficial effects of probiotics in preventing and treating certain diseases as well as current and future perspectives of probiotic research.http://www.sciencedirect.com/science/article/pii/S2213453015000300ProbioticHeath benefitsBile salt hydrolaseDysbiosisMicrobiome |
| spellingShingle | Eric Banan-Mwine Daliri Byong H. Lee New perspectives on probiotics in health and disease Food Science and Human Wellness Probiotic Heath benefits Bile salt hydrolase Dysbiosis Microbiome |
| title | New perspectives on probiotics in health and disease |
| title_full | New perspectives on probiotics in health and disease |
| title_fullStr | New perspectives on probiotics in health and disease |
| title_full_unstemmed | New perspectives on probiotics in health and disease |
| title_short | New perspectives on probiotics in health and disease |
| title_sort | new perspectives on probiotics in health and disease |
| topic | Probiotic Heath benefits Bile salt hydrolase Dysbiosis Microbiome |
| url | http://www.sciencedirect.com/science/article/pii/S2213453015000300 |
| work_keys_str_mv | AT ericbananmwinedaliri newperspectivesonprobioticsinhealthanddisease AT byonghlee newperspectivesonprobioticsinhealthanddisease |