ML210 Antagonizes ABCB1- Not ABCG2-Mediated Multidrug Resistance in Colorectal Cancer

ML210 Antagonizes ABCB1- Not ABCG2-Mediated Multidrug Resistance in Colorectal Cancer

<b>Objectives:</b> ABCB1-mediated multidrug resistance (MDR) compromises chemotherapy efficacy in colorectal cancer (CRC). Despite decades of research, no selective ABCB1 inhibitor has achieved clinical success. This study investigates ML210 as a novel ABCB1-specific inhibitor to reverse...

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Bibliographic Details
Main Authors:	Yan-Chi Li, Yu-Meng Xiong, Ze-Ping Long, Yi-Ping Huang, Yu-Bin Shu, Ke He, Hong-Yan Sun, Zhi Shi
Format:	Article
Language:	English
Published:	MDPI AG 2025-05-01
Series:	Biomedicines
Subjects:	colorectal cancer multidrug resistance ABCB1 ABCG2 ML210
Online Access:	https://www.mdpi.com/2227-9059/13/5/1245
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