Automatic target-seeking nanoparticle inhibiting orthotopic drug-resistant colon cancer and liver metastases via regulating cancer cell adhesion and proliferation
Abstract Galectin-3 (Gal-3) plays an important role in adhesion and proliferation of cancer cells. The level of Gal-3 in blood and the expression of Gal-3 in colon cancer tissue are significantly increased in patient with colon cancer. The elevated Gal-3 promotes the migration and drug resistance of...
Saved in:
| Main Authors: | Shaobo Bai, Yang Sun, Miao Liu, Ying Cheng, Qifeng Ji, Bangle Zhang, Zhifu Yang, Siyuan Zhou, Daozhou Liu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-06-01
|
| Series: | Journal of Nanobiotechnology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12951-025-03422-x |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
RETRACTED: Paris saponin VII enhanced the sensitivity of HepG2/ADR cells to ADR via modulation of PI3K/AKT/MAPK signaling pathway
by: Gong‐En Tang, et al.
Published: (2020-02-01) -
Paris saponin VII attenuates psoriasiform inflammation by regulating STAT3/NFκB signaling pathway and Caspase-1-induced pyroptosis
by: Xiangnan Zhou, et al.
Published: (2025-05-01) -
Galectins, antibodies to them and galectin-3 binding protein in systemic lupus erythematosus
by: L. V. Kondratyeva, et al.
Published: (2025-03-01) -
Galectin-1 and Galectin-3 expression in colon cancer and its correlation with tumor invasion, differentiation, and metastatic spread
by: Yu. V. Kolobovnikova, et al.
Published: (2021-12-01) -
Galectins: a potential pharmacological target
by: V. A. Serebryakova, et al.
Published: (2024-10-01)