Recurrent waning of anti-SARS-CoV-2 neutralizing antibodies despite multiple antigen encounters

Recurrent waning of anti-SARS-CoV-2 neutralizing antibodies despite multiple antigen encounters

Abstract Background SARS-CoV-2 neutralizing antibodies may protect against symptomatic infection in immunized individuals. However, vaccine-induced antibody levels wane over time, reducing vaccine efficacy. The definition of the waning kinetics of neutralizing SARS-CoV-2 responses and the potential...

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Main Authors: Edwards Pradenas, Victor Urrea, Silvia Marfil, Tetyana Pidkova, Carmen Aguilar-Gurrieri, Ferran Abancó, Lourdes Mateu, Anna Chamorro, Eulàlia Grau, Macedonia Trigueros, Jorge Carrillo, Marta Massanella, Benjamin Trinité, Bonaventura Clotet, Julià Blanco
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Journal of Translational Medicine
Subjects:
COVID-19
Neutralization
Kinetics
Humoral response
Hybrid immunity
Vaccine
Online Access:https://doi.org/10.1186/s12967-025-06837-0
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