Unraveling C-to-U RNA editing events from direct RNA sequencing

Unraveling C-to-U RNA editing events from direct RNA sequencing

In mammals, RNA editing events involve the conversion of adenosine (A) in inosine (I) by ADAR enzymes or the hydrolytic deamination of cytosine (C) in uracil (U) by the APOBEC family of enzymes, mostly APOBEC1. RNA editing has a plethora of biological functions, and its deregulation has been associa...

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Bibliographic Details
Main Authors: Adriano Fonzino, Caterina Manzari, Paola Spadavecchia, Uday Munagala, Serena Torrini, Silvestro Conticello, Graziano Pesole, Ernesto Picardi
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:RNA Biology
Subjects:
Direct RNA sequencing
RNA editing
iForest
RNA modifications
C-to-U editing
Online Access:https://www.tandfonline.com/doi/10.1080/15476286.2023.2290843
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