Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate

By-products (phenyl salicylate, phenyl 4-hydroxybenzoate, and xanthone) from transesterification between phenol and dimethyl carbonate (DMC) were qualitatively analyzed by gas chromatography-mass spectrometry, and a gas chromatographic method with directed injection for simultaneous quantitative ana...

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Main Authors: Tao Liu, Jing Hu, Li Yong, Gang Zhang, Yi Zhang, Tong Chen, Gongying Wang
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2019/7632520
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author Tao Liu
Jing Hu
Li Yong
Gang Zhang
Yi Zhang
Tong Chen
Gongying Wang
author_facet Tao Liu
Jing Hu
Li Yong
Gang Zhang
Yi Zhang
Tong Chen
Gongying Wang
author_sort Tao Liu
collection DOAJ
description By-products (phenyl salicylate, phenyl 4-hydroxybenzoate, and xanthone) from transesterification between phenol and dimethyl carbonate (DMC) were qualitatively analyzed by gas chromatography-mass spectrometry, and a gas chromatographic method with directed injection for simultaneous quantitative analysis of the product (DPC) and by-products of the transesterification has been established. Based on the results of qualitative and quantitative analyses, the mechanism of the by-products generation was preliminarily deduced. The sample for quantitative analysis was directly diluted in acetone, and related compounds were separated on an HP-5 capillary column and detected by a hydrogen flame ionization detector (FID). The product and by-products were well separated, the correlation coefficients (r) within the concentration range of 1.0 μg/mL–100 μg/mL were ≥0.9997, the relative standard deviations were between 0.5% and 4.4%, spiked recoveries were between 91.5% and 105.6%, and detection limits were between 0.11 and 0.18 μg/mL. The established method is simple, rapid, accurate, sensitive, and highly specific. It is suitable for simultaneous qualitative and quantitative analyses of the product and by-products of transesterification between phenol and DMC.
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institution Kabale University
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language English
publishDate 2019-01-01
publisher Wiley
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series Journal of Analytical Methods in Chemistry
spelling doaj-art-2066f7eaf9fa47fa86d650850ac71efd2025-08-20T03:54:43ZengWileyJournal of Analytical Methods in Chemistry2090-88652090-88732019-01-01201910.1155/2019/76325207632520Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl CarbonateTao Liu0Jing Hu1Li Yong2Gang Zhang3Yi Zhang4Tong Chen5Gongying Wang6Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaSichuan Center for Disease Control and Prevention, Chengdu 610041, ChinaChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaChengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu 610041, ChinaBy-products (phenyl salicylate, phenyl 4-hydroxybenzoate, and xanthone) from transesterification between phenol and dimethyl carbonate (DMC) were qualitatively analyzed by gas chromatography-mass spectrometry, and a gas chromatographic method with directed injection for simultaneous quantitative analysis of the product (DPC) and by-products of the transesterification has been established. Based on the results of qualitative and quantitative analyses, the mechanism of the by-products generation was preliminarily deduced. The sample for quantitative analysis was directly diluted in acetone, and related compounds were separated on an HP-5 capillary column and detected by a hydrogen flame ionization detector (FID). The product and by-products were well separated, the correlation coefficients (r) within the concentration range of 1.0 μg/mL–100 μg/mL were ≥0.9997, the relative standard deviations were between 0.5% and 4.4%, spiked recoveries were between 91.5% and 105.6%, and detection limits were between 0.11 and 0.18 μg/mL. The established method is simple, rapid, accurate, sensitive, and highly specific. It is suitable for simultaneous qualitative and quantitative analyses of the product and by-products of transesterification between phenol and DMC.http://dx.doi.org/10.1155/2019/7632520
spellingShingle Tao Liu
Jing Hu
Li Yong
Gang Zhang
Yi Zhang
Tong Chen
Gongying Wang
Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
Journal of Analytical Methods in Chemistry
title Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
title_full Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
title_fullStr Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
title_full_unstemmed Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
title_short Qualitative and Quantitative Analysis of the Product and By-Products from Transesterification between Phenol and Dimethyl Carbonate
title_sort qualitative and quantitative analysis of the product and by products from transesterification between phenol and dimethyl carbonate
url http://dx.doi.org/10.1155/2019/7632520
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