Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy

The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful...

Full description

Saved in:
Bibliographic Details
Main Author: E. V. Igolkina
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2014-09-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/563
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849339333229674496
author E. V. Igolkina
author_facet E. V. Igolkina
author_sort E. V. Igolkina
collection DOAJ
description The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful investigation and dispute. The paper gives the results of studies of the neurogenic component of pain in OA patients. There is sufficient evidence for the presence of sensory anomalies accompanying pain in OA. The clinical use of questionnaires to detect neuropathic pain may assist in identifying central sensitization in patients with OA. Medicaments for the symptomatic therapy of pain are characterized.
format Article
id doaj-art-2062903cc2554751bcf17d5b9f8f9e17
institution Kabale University
issn 1996-7012
2310-158X
language Russian
publishDate 2014-09-01
publisher IMA-PRESS LLC
record_format Article
series Современная ревматология
spelling doaj-art-2062903cc2554751bcf17d5b9f8f9e172025-08-20T03:44:10ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2014-09-0183667210.14412/1996-7012-2014-3-66-721864Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapyE. V. Igolkina0I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia 8, Trubetskaya St., Build. 2, Moscow 101000The paper outlines the current views on mechanisms for pain development in osteoarthrosis (OA). The problem of analgesia in OA remains to be solved, which gives rise to a more careful study of the mechanisms in OA. Whether peripheral somatosensory nerve damage occurs in OA is the subject of careful investigation and dispute. The paper gives the results of studies of the neurogenic component of pain in OA patients. There is sufficient evidence for the presence of sensory anomalies accompanying pain in OA. The clinical use of questionnaires to detect neuropathic pain may assist in identifying central sensitization in patients with OA. Medicaments for the symptomatic therapy of pain are characterized.https://mrj.ima-press.net/mrj/article/view/563painosteoarthrosisnociceptionneuropathic painpain treatment
spellingShingle E. V. Igolkina
Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
Современная ревматология
pain
osteoarthrosis
nociception
neuropathic pain
pain treatment
title Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_full Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_fullStr Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_full_unstemmed Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_short Current views of the development of pain syndrome mechanisms in patients with osteoarthrosis. Rational pharmacotherapy
title_sort current views of the development of pain syndrome mechanisms in patients with osteoarthrosis rational pharmacotherapy
topic pain
osteoarthrosis
nociception
neuropathic pain
pain treatment
url https://mrj.ima-press.net/mrj/article/view/563
work_keys_str_mv AT evigolkina currentviewsofthedevelopmentofpainsyndromemechanismsinpatientswithosteoarthrosisrationalpharmacotherapy