The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis
MicroRNAs, small noncoding RNA molecules, are critical in modulating gene expression and contribute substantially to the initiation and progression of urinary bladder cancer (UBCa), a major malignancy affecting people globally. UBCa is known for its high recurrence rates and significant heterogeneit...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | Indian Journal of Urology |
| Online Access: | https://journals.lww.com/10.4103/iju.iju_442_24 |
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| author | Rachana Tripathy Lalit Kumar Sukhad Kural Anuja Thakur Sameer Trivedi Satya Narayan Sankhwar |
| author_facet | Rachana Tripathy Lalit Kumar Sukhad Kural Anuja Thakur Sameer Trivedi Satya Narayan Sankhwar |
| author_sort | Rachana Tripathy |
| collection | DOAJ |
| description | MicroRNAs, small noncoding RNA molecules, are critical in modulating gene expression and contribute substantially to the initiation and progression of urinary bladder cancer (UBCa), a major malignancy affecting people globally. UBCa is known for its high recurrence rates and significant heterogeneity. The stability of miRNAs in body fluids such as urine and blood are excellent potential noninvasive markers for early detection, monitoring treatment progress, and predicting outcomes of patients with UBCa. In addition, miRNAs could also improve the effectiveness of immunotherapy and support the development of personalized treatment strategies. Despite their significant potential, challenges such as variability in the expression of miRNAs and shortcomings in their delivery systems must be carefully addressed. This strength, weakness, opportunity, and threat (SWOT) analysis highlights the crucial role of miRNAs in UBCa and explores their potential in advancing precision oncology. |
| format | Article |
| id | doaj-art-205e7eef0ee84e3dbbce2cdfd26ddadd |
| institution | Kabale University |
| issn | 0970-1591 1998-3824 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Urology |
| spelling | doaj-art-205e7eef0ee84e3dbbce2cdfd26ddadd2025-08-20T03:24:43ZengWolters Kluwer Medknow PublicationsIndian Journal of Urology0970-15911998-38242025-04-014129810310.4103/iju.iju_442_24The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysisRachana TripathyLalit KumarSukhad KuralAnuja ThakurSameer TrivediSatya Narayan SankhwarMicroRNAs, small noncoding RNA molecules, are critical in modulating gene expression and contribute substantially to the initiation and progression of urinary bladder cancer (UBCa), a major malignancy affecting people globally. UBCa is known for its high recurrence rates and significant heterogeneity. The stability of miRNAs in body fluids such as urine and blood are excellent potential noninvasive markers for early detection, monitoring treatment progress, and predicting outcomes of patients with UBCa. In addition, miRNAs could also improve the effectiveness of immunotherapy and support the development of personalized treatment strategies. Despite their significant potential, challenges such as variability in the expression of miRNAs and shortcomings in their delivery systems must be carefully addressed. This strength, weakness, opportunity, and threat (SWOT) analysis highlights the crucial role of miRNAs in UBCa and explores their potential in advancing precision oncology.https://journals.lww.com/10.4103/iju.iju_442_24 |
| spellingShingle | Rachana Tripathy Lalit Kumar Sukhad Kural Anuja Thakur Sameer Trivedi Satya Narayan Sankhwar The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis Indian Journal of Urology |
| title | The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis |
| title_full | The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis |
| title_fullStr | The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis |
| title_full_unstemmed | The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis |
| title_short | The current status of miRNA in urinary bladder cancer: A minireview and strength, weakness, opportunity, and threat analysis |
| title_sort | current status of mirna in urinary bladder cancer a minireview and strength weakness opportunity and threat analysis |
| url | https://journals.lww.com/10.4103/iju.iju_442_24 |
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