PATHOLOGICAL EFFECT OF TOXOCARA CANIS EGG DOSES IN EXPERIMENTAL MICE.

In this study we examined the effect of various sensitizing doses of infective Toxocara canis eggs and the trapping of larvae in different tissues of the murine host. The level of trapping increased with sensitization egg doses. Different doses of Toxocara canis eggs were given to ten groups each wi...

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Bibliographic Details
Main Authors: Hind J. Mahmood, Wisam M. Al-Saeed
Format: Article
Language:English
Published: College of Veterinary Medicine, University of Basrah, Iraq 2011-06-01
Series:Basrah Journal of Veterinary Research
Subjects:
Online Access:https://bjvr.uobasrah.edu.iq/article_59748_a8d2501be4b1c9cb3472fc46d91b074e.pdf
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Summary:In this study we examined the effect of various sensitizing doses of infective Toxocara canis eggs and the trapping of larvae in different tissues of the murine host. The level of trapping increased with sensitization egg doses. Different doses of Toxocara canis eggs were given to ten groups each with five mice and then necropsied after different periods. Experimental toxocariasis in mice sacrificed at (1,2 and 3) weeks post infection showed no lesions in mice given 50, 75 and 100 Toxocara canis eggs respectively. Other groups given higher doses of T.canis eggs between (125-500 eggs) showed lesions in liver, lungs, eyes and muscles of sacrificed mice after 4 weeks of infection.
ISSN:1813-8497
2410-8456