Pediatric follicular lymphoma: literature review and presentation of a rare clinical case

Follicular lymphoma is one of the most common non-Hodgkin’s lymphomas in adults. One of the rather rare variants of follicular lymphoma is pediatric follicular lymphoma. This variant, despite the name, is diagnosed not only in children, but also among young adults. Pediatric follicular lymphoma is c...

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Main Authors: A. S. Volkova, T. T. Valiev, D. S. Abramov, A. V. Tarakanova, A. A. Odzharova, Yu. E. Ryabukhina, P. A. Zeynalova
Format: Article
Language:Russian
Published: ABV-press 2024-09-01
Series:Онкогематология
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Online Access:https://oncohematology.abvpress.ru/ongm/article/view/943
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author A. S. Volkova
T. T. Valiev
D. S. Abramov
A. V. Tarakanova
A. A. Odzharova
Yu. E. Ryabukhina
P. A. Zeynalova
author_facet A. S. Volkova
T. T. Valiev
D. S. Abramov
A. V. Tarakanova
A. A. Odzharova
Yu. E. Ryabukhina
P. A. Zeynalova
author_sort A. S. Volkova
collection DOAJ
description Follicular lymphoma is one of the most common non-Hodgkin’s lymphomas in adults. One of the rather rare variants of follicular lymphoma is pediatric follicular lymphoma. This variant, despite the name, is diagnosed not only in children, but also among young adults. Pediatric follicular lymphoma is characterized by early (I, II) stages, the absence or weak BCL2 expression, and the predominant absence of t(14;18)(q32;q21) translocation. Treatment tactics vary widely from radical surgical tumor resection with subsequent follow-up to chemoimmunotherapy with rituximab.This article presents a clinical case of advanced pediatric follicular lymphoma (stage III) in a 5-year-old patient. Using a combined treatment approach (surgery followed by immunochemotherapy) allowed to achieve a complete metabolic response which lasts more than a year.
format Article
id doaj-art-204515fbf08e4c2b9255d2126ccf3555
institution Kabale University
issn 1818-8346
2413-4023
language Russian
publishDate 2024-09-01
publisher ABV-press
record_format Article
series Онкогематология
spelling doaj-art-204515fbf08e4c2b9255d2126ccf35552025-08-20T04:00:14ZrusABV-pressОнкогематология1818-83462413-40232024-09-0119312213110.17650/1818-8346-2024-19-3-122-131770Pediatric follicular lymphoma: literature review and presentation of a rare clinical caseA. S. Volkova0T. T. Valiev1D. S. Abramov2A. V. Tarakanova3A. A. Odzharova4Yu. E. Ryabukhina5P. A. Zeynalova6N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia; I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University)Dmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of RussiaDmitry Rogachev National Medical Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of RussiaN.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaClinical Hospital “Lapino” of the “Mother and Child” Group of companiesI.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia (Sechenov University); Clinical Hospital “Lapino” of the “Mother and Child” Group of companiesFollicular lymphoma is one of the most common non-Hodgkin’s lymphomas in adults. One of the rather rare variants of follicular lymphoma is pediatric follicular lymphoma. This variant, despite the name, is diagnosed not only in children, but also among young adults. Pediatric follicular lymphoma is characterized by early (I, II) stages, the absence or weak BCL2 expression, and the predominant absence of t(14;18)(q32;q21) translocation. Treatment tactics vary widely from radical surgical tumor resection with subsequent follow-up to chemoimmunotherapy with rituximab.This article presents a clinical case of advanced pediatric follicular lymphoma (stage III) in a 5-year-old patient. Using a combined treatment approach (surgery followed by immunochemotherapy) allowed to achieve a complete metabolic response which lasts more than a year.https://oncohematology.abvpress.ru/ongm/article/view/943follicular lymphomapediatric type follicular lymphomaoncologyhematologydiagnosistreatmentimmunochemotherapysurgery
spellingShingle A. S. Volkova
T. T. Valiev
D. S. Abramov
A. V. Tarakanova
A. A. Odzharova
Yu. E. Ryabukhina
P. A. Zeynalova
Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
Онкогематология
follicular lymphoma
pediatric type follicular lymphoma
oncology
hematology
diagnosis
treatment
immunochemotherapy
surgery
title Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
title_full Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
title_fullStr Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
title_full_unstemmed Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
title_short Pediatric follicular lymphoma: literature review and presentation of a rare clinical case
title_sort pediatric follicular lymphoma literature review and presentation of a rare clinical case
topic follicular lymphoma
pediatric type follicular lymphoma
oncology
hematology
diagnosis
treatment
immunochemotherapy
surgery
url https://oncohematology.abvpress.ru/ongm/article/view/943
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AT avtarakanova pediatricfollicularlymphomaliteraturereviewandpresentationofarareclinicalcase
AT aaodzharova pediatricfollicularlymphomaliteraturereviewandpresentationofarareclinicalcase
AT yueryabukhina pediatricfollicularlymphomaliteraturereviewandpresentationofarareclinicalcase
AT pazeynalova pediatricfollicularlymphomaliteraturereviewandpresentationofarareclinicalcase