Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease.

Evaluating the quality of research into a single prognostic biomarker: a systematic review and meta-analysis of 83 studies of C-reactive protein in stable coronary artery disease.

<h4>Background</h4>Systematic evaluations of the quality of research on a single prognostic biomarker are rare. We sought to evaluate the quality of prognostic research evidence for the association of C-reactive protein (CRP) with fatal and nonfatal events among patients with stable coro...

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Main Authors: Harry Hemingway, Peter Philipson, Ruoling Chen, Natalie K Fitzpatrick, Jacqueline Damant, Martin Shipley, Keith R Abrams, Santiago Moreno, Kate S L McAllister, Stephen Palmer, Juan Carlos Kaski, Adam D Timmis, Aroon D Hingorani
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-06-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1000286&type=printable
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