Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations

Introduction Excessive drinking and depression are frequently comorbid and make a substantial contribution to the global non-communicable disease burden. A range of effective interventions and treatments exist for either excessive drinking or depression alone, including a positive emerging evidence...

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Main Authors: Eileen F S Kaner, Bernd Schulte, Fiona Beyer, Christiane S Schmidt, Amy O'Donnell
Format: Article
Language:English
Published: BMJ Publishing Group 2019-10-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/9/10/e031503.full
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author Eileen F S Kaner
Bernd Schulte
Fiona Beyer
Christiane S Schmidt
Amy O'Donnell
author_facet Eileen F S Kaner
Bernd Schulte
Fiona Beyer
Christiane S Schmidt
Amy O'Donnell
author_sort Eileen F S Kaner
collection DOAJ
description Introduction Excessive drinking and depression are frequently comorbid and make a substantial contribution to the global non-communicable disease burden. A range of effective interventions and treatments exist for either excessive drinking or depression alone, including a positive emerging evidence base for the use of digital interventions. Computerised and/or smartphone delivered advice could provide flexible, coordinated support for patients with comorbid excessive drinking and depression. However, to date, no systematic review of the evidence has been conducted focused on the effectiveness of digital interventions for this specific comorbid population. This systematic review will identify and evaluate the effectiveness of digital interventions for reducing comorbid excessive drinking and depression in community-dwelling populations.Methods and analysis We will search MEDLINE, The Cochrane Library, CENTRAL, CINAHL, PsycINFO, ERIC and SCI from inception to end of July 2019 for randomised controlled trials that evaluate any personalised digital intervention for comorbid excessive drinking and depression and published in any language. Primary outcomes will be changes in quantity of alcohol consumed and depressive symptoms. Screening, data extraction and risk of bias assessment will be undertaken independently by two reviewers, with disagreements resolved through discussion. Meta-analytic methods will be used to synthesise the data collected relating to the primary outcomes of interest.Ethics and dissemination As a systematic review, ethical approval is not needed. Findings will be published in peer-reviewed journals and presented at conferences.Trial registration number CRD42019130134.
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spelling doaj-art-2025acd2c2434496b4f4f37be8c67dce2025-08-20T01:56:35ZengBMJ Publishing GroupBMJ Open2044-60552019-10-0191010.1136/bmjopen-2019-031503Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populationsEileen F S Kaner0Bernd Schulte1Fiona Beyer2Christiane S Schmidt3Amy O'Donnell4Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UKDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyNational Institute for Health Research (NIHR) Older People and Frailty Policy Research Unit, Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK1 Centre of Interdisciplinary Addiction Research (ZIS), Department of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, Hamburg, GermanyNIHR Policy Research Unit in Behavioural Science, Newcastle University, Newcastle upon Tyne, UKIntroduction Excessive drinking and depression are frequently comorbid and make a substantial contribution to the global non-communicable disease burden. A range of effective interventions and treatments exist for either excessive drinking or depression alone, including a positive emerging evidence base for the use of digital interventions. Computerised and/or smartphone delivered advice could provide flexible, coordinated support for patients with comorbid excessive drinking and depression. However, to date, no systematic review of the evidence has been conducted focused on the effectiveness of digital interventions for this specific comorbid population. This systematic review will identify and evaluate the effectiveness of digital interventions for reducing comorbid excessive drinking and depression in community-dwelling populations.Methods and analysis We will search MEDLINE, The Cochrane Library, CENTRAL, CINAHL, PsycINFO, ERIC and SCI from inception to end of July 2019 for randomised controlled trials that evaluate any personalised digital intervention for comorbid excessive drinking and depression and published in any language. Primary outcomes will be changes in quantity of alcohol consumed and depressive symptoms. Screening, data extraction and risk of bias assessment will be undertaken independently by two reviewers, with disagreements resolved through discussion. Meta-analytic methods will be used to synthesise the data collected relating to the primary outcomes of interest.Ethics and dissemination As a systematic review, ethical approval is not needed. Findings will be published in peer-reviewed journals and presented at conferences.Trial registration number CRD42019130134.https://bmjopen.bmj.com/content/9/10/e031503.full
spellingShingle Eileen F S Kaner
Bernd Schulte
Fiona Beyer
Christiane S Schmidt
Amy O'Donnell
Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
BMJ Open
title Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
title_full Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
title_fullStr Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
title_full_unstemmed Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
title_short Study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community-dwelling populations
title_sort study protocol for a systematic review of evidence for digital interventions for comorbid excessive drinking and depression in community dwelling populations
url https://bmjopen.bmj.com/content/9/10/e031503.full
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