Clinical benefits of immune checkpoint inhibitors for malignant peripheral nerve sheath tumors with NF2 mutation: a case report

Clinical benefits of immune checkpoint inhibitors for malignant peripheral nerve sheath tumors with NF2 mutation: a case report

BackgroundMalignant peripheral nerve sheath tumors (MPNSTs), which arise from peripheral nerves or cells associated with nerve sheaths, are uncommon and biologically aggressive sarcomas. Currently, immune checkpoint inhibitors (ICIs) have exhibited antitumor efficiency in various sarcomas. However,...

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Bibliographic Details
Main Authors: Yale Jiang, Guo Zhao, Qiyu Tang, Shujun Xing, Shuhang Wang, Ning Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
MPNSTs
immune checkpoint inhibitors
immunotherapy
case report
rare cancer
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1596348/full
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