Anti-biofilm and anti-quorum sensing activities of galloylquinic acid against clinical isolates of multidrug-resistant Pseudomonas aeruginosa in open wound infection: in vitro and in vivo efficacy studies

Anti-biofilm and anti-quorum sensing activities of galloylquinic acid against clinical isolates of multidrug-resistant Pseudomonas aeruginosa in open wound infection: in vitro and in vivo efficacy studies

Abstract Background Pseudomonas aeruginosa can proliferate in immunocompromised individuals, forming biofilms that increase antibiotic resistance. This bacterium poses a significant global health risk due to its resistance to human defenses, antibiotics, and various environmental stresses. The objec...

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Bibliographic Details
Main Authors: Lamiaa A. Al-Maddboly, Mohamed Abd El-Salam, Jairo K. Bastos, Eiman A. Hasby, Ivan Kushkevych, Rasha M. El-Morsi
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Microbiology
Subjects:
Antibacterial
Pseudomonas aeruginosa
Anti-biofilm
Galloylquinic acid compounds
Online Access:https://doi.org/10.1186/s12866-024-03712-8
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