Hematological Changes Provoked by Natural Alkaloids
Background and aims: Plant alkaloids are naturally occurring nitrogen-containing chemicals with a wide range of therapeutic applications. They have been reported to cure a considerable number of illnesses, including cancer, diabetes, malaria, and heart dysfunction. This study sought to evaluate t...
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| Format: | Article |
| Language: | English |
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Shahrekord University of Medical Sciences
2024-12-01
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| Series: | Future Natural Products |
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| Online Access: | http://fnp.skums.ac.ir/Article/fnp-167 |
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| author | Olubayode Bamidele Abigail Oluwatomisin Popoola Lawrence Dayo Adedayo Funmilola Adelowo David Inaolaji Dennis Seyi Arokoyo |
| author_facet | Olubayode Bamidele Abigail Oluwatomisin Popoola Lawrence Dayo Adedayo Funmilola Adelowo David Inaolaji Dennis Seyi Arokoyo |
| author_sort | Olubayode Bamidele |
| collection | DOAJ |
| description | Background and aims: Plant alkaloids are naturally occurring nitrogen-containing chemicals
with a wide range of therapeutic applications. They have been reported to cure a considerable
number of illnesses, including cancer, diabetes, malaria, and heart dysfunction. This study
sought to evaluate the impact of several plant alkaloids on hematological parameters in animals.
Methods: The results of different plant extracts containing alkaloids in laboratory animals on
hematological indices such as red blood cell (RBC) count, hemoglobin (Hb) concentration,
hematocrit (Hct), white blood cell count, platelet count, and others using normal laboratory
methods were gathered from scientific papers and databases using keywords such as plant
alkaloids, alkaloid toxicity, hematological parameters, hematological changes, blood, and
animals.
Results: Plant alkaloids identified through the search had different impacts on hematological
indices. Some alkaloids raised RBC count, Hb concentration, and Hct, while others lowered these
values. Platelet count was generally observed to increase, but there were exceptions. Certain
alkaloids found in some plants have no substantial influence on hematological parameters.
Conclusion: Plant alkaloids can cause various changes in hematological parameters in animals.
These alterations might be useful or deleterious depending on the alkaloid and its concentration.
Understanding these effects is essential for the safe and effective use of plant-based therapies. |
| format | Article |
| id | doaj-art-20056ad5455048bfa3cf7cfd85f04490 |
| institution | Kabale University |
| issn | 2783-4662 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Shahrekord University of Medical Sciences |
| record_format | Article |
| series | Future Natural Products |
| spelling | doaj-art-20056ad5455048bfa3cf7cfd85f044902025-01-13T09:45:44ZengShahrekord University of Medical SciencesFuture Natural Products2783-46622024-12-01101445110.34172/fnp.167Hematological Changes Provoked by Natural AlkaloidsOlubayode Bamidele0https://orcid.org/0000-0002-8591-034XAbigail Oluwatomisin Popoola1https://orcid.org/0009-0004-0911-6250Lawrence Dayo Adedayo2https://orcid.org/0000-0002-2686-9009Funmilola Adelowo3https://orcid.org/0009-0006-4535-1340David Inaolaji4https://orcid.org/0009-0002-1383-1498Dennis Seyi Arokoyo5https://orcid.org/0000-0001-8975-5300Physiology Department, College of Health Sciences, Bowen University, Iwo, NigeriaPhysiology Department, College of Health Sciences, Bowen University, Iwo, NigeriaPhysiology Department, College of Health Sciences, Bowen University, Iwo, NigeriaPhysiology Department, College of Health Sciences, Bowen University, Iwo, NigeriaPhysiology Department, College of Health Sciences, Bowen University, Iwo, NigeriaDepartment of Physiology, Osun State University, Osogbo, Osun State, NigeriaBackground and aims: Plant alkaloids are naturally occurring nitrogen-containing chemicals with a wide range of therapeutic applications. They have been reported to cure a considerable number of illnesses, including cancer, diabetes, malaria, and heart dysfunction. This study sought to evaluate the impact of several plant alkaloids on hematological parameters in animals. Methods: The results of different plant extracts containing alkaloids in laboratory animals on hematological indices such as red blood cell (RBC) count, hemoglobin (Hb) concentration, hematocrit (Hct), white blood cell count, platelet count, and others using normal laboratory methods were gathered from scientific papers and databases using keywords such as plant alkaloids, alkaloid toxicity, hematological parameters, hematological changes, blood, and animals. Results: Plant alkaloids identified through the search had different impacts on hematological indices. Some alkaloids raised RBC count, Hb concentration, and Hct, while others lowered these values. Platelet count was generally observed to increase, but there were exceptions. Certain alkaloids found in some plants have no substantial influence on hematological parameters. Conclusion: Plant alkaloids can cause various changes in hematological parameters in animals. These alterations might be useful or deleterious depending on the alkaloid and its concentration. Understanding these effects is essential for the safe and effective use of plant-based therapies.http://fnp.skums.ac.ir/Article/fnp-167alkaloidsplantshematological changesbloodtoxicityanimals |
| spellingShingle | Olubayode Bamidele Abigail Oluwatomisin Popoola Lawrence Dayo Adedayo Funmilola Adelowo David Inaolaji Dennis Seyi Arokoyo Hematological Changes Provoked by Natural Alkaloids Future Natural Products alkaloids plants hematological changes blood toxicity animals |
| title | Hematological Changes Provoked by Natural Alkaloids |
| title_full | Hematological Changes Provoked by Natural Alkaloids |
| title_fullStr | Hematological Changes Provoked by Natural Alkaloids |
| title_full_unstemmed | Hematological Changes Provoked by Natural Alkaloids |
| title_short | Hematological Changes Provoked by Natural Alkaloids |
| title_sort | hematological changes provoked by natural alkaloids |
| topic | alkaloids plants hematological changes blood toxicity animals |
| url | http://fnp.skums.ac.ir/Article/fnp-167 |
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