Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice
Abstract Objective To evaluate the clinical efficacy of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice, focusing on improvements in liver function, bile duct patency time, and reduction of postoperative complic...
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BMC
2025-03-01
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| Series: | BMC Surgery |
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| Online Access: | https://doi.org/10.1186/s12893-025-02807-x |
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| author | Shoulin Zhang Shaopeng Huang Zheng Xing Youwen Song Fujian Yuan |
| author_facet | Shoulin Zhang Shaopeng Huang Zheng Xing Youwen Song Fujian Yuan |
| author_sort | Shoulin Zhang |
| collection | DOAJ |
| description | Abstract Objective To evaluate the clinical efficacy of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice, focusing on improvements in liver function, bile duct patency time, and reduction of postoperative complications. Methods 181 patients with malignant obstructive jaundice were retrospectively selected from a hospital in Ganzhou City, Jiangxi Province, from April 2021 to May 2024, of which 132 underwent routine percutaneous liver puncture biliary drainage and 49 underwent percutaneous liver puncture biliary drainage combined with metal stent implantation as the observation group. Results The clinical efficacy of the observation group was higher (P < 0.05), and the bile duct patency time was longer (P < 0.05). The AST, ALT, DBIL and TBIL levels were decreased 1 week and 1 month after surgery, and the decrease was more significant in the observation group (P < 0.05). In addition, the incidence of postoperative complications (bile duct infection and electrolyte disturbance) in the observation group was lower (P < 0.05). Conclusion Percutaneous hepatic puncture biliary drainage combined with metal stent implantation has significant clinical efficacy, which can effectively improve the clinical symptoms of patients, prolong the biliary patency time, reduce the level of bilirubin, promote the improvement of liver function, and lower the incidence of postoperative complications. Clinical trial number not applicable. |
| format | Article |
| id | doaj-art-1ffe9241ec954e68ac9c2feb990b65cf |
| institution | DOAJ |
| issn | 1471-2482 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Surgery |
| spelling | doaj-art-1ffe9241ec954e68ac9c2feb990b65cf2025-08-20T02:49:29ZengBMCBMC Surgery1471-24822025-03-012511710.1186/s12893-025-02807-xClinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundiceShoulin Zhang0Shaopeng Huang1Zheng Xing2Youwen Song3Fujian Yuan4Department of Interventional Therapy, Ganzhou Cancer HospitalDepartment of Oncology, Ganzhou Dayu County People’s HospitalDepartment of Interventional Therapy, Ganzhou Cancer HospitalDepartment of Interventional Therapy, Ganzhou Cancer HospitalDepartment of Interventional Therapy, Ganzhou Cancer HospitalAbstract Objective To evaluate the clinical efficacy of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice, focusing on improvements in liver function, bile duct patency time, and reduction of postoperative complications. Methods 181 patients with malignant obstructive jaundice were retrospectively selected from a hospital in Ganzhou City, Jiangxi Province, from April 2021 to May 2024, of which 132 underwent routine percutaneous liver puncture biliary drainage and 49 underwent percutaneous liver puncture biliary drainage combined with metal stent implantation as the observation group. Results The clinical efficacy of the observation group was higher (P < 0.05), and the bile duct patency time was longer (P < 0.05). The AST, ALT, DBIL and TBIL levels were decreased 1 week and 1 month after surgery, and the decrease was more significant in the observation group (P < 0.05). In addition, the incidence of postoperative complications (bile duct infection and electrolyte disturbance) in the observation group was lower (P < 0.05). Conclusion Percutaneous hepatic puncture biliary drainage combined with metal stent implantation has significant clinical efficacy, which can effectively improve the clinical symptoms of patients, prolong the biliary patency time, reduce the level of bilirubin, promote the improvement of liver function, and lower the incidence of postoperative complications. Clinical trial number not applicable.https://doi.org/10.1186/s12893-025-02807-xPercutaneous hepatic puncture biliary drainageMetal stent implantationMalignant obstructive jaundice |
| spellingShingle | Shoulin Zhang Shaopeng Huang Zheng Xing Youwen Song Fujian Yuan Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice BMC Surgery Percutaneous hepatic puncture biliary drainage Metal stent implantation Malignant obstructive jaundice |
| title | Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| title_full | Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| title_fullStr | Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| title_full_unstemmed | Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| title_short | Clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| title_sort | clinical effect of percutaneous hepatic puncture biliary drainage combined with metal stent implantation in the treatment of malignant obstructive jaundice |
| topic | Percutaneous hepatic puncture biliary drainage Metal stent implantation Malignant obstructive jaundice |
| url | https://doi.org/10.1186/s12893-025-02807-x |
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