Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease

A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was b...

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Main Authors: Jian Zhuang, Shushui Wang, Zhiwei Zhang, Shaoying Zeng, Yunzhen Shi, Shaohan Nong
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2008-02-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2387
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author Jian Zhuang
Shushui Wang
Zhiwei Zhang
Shaoying Zeng
Yunzhen Shi
Shaohan Nong
author_facet Jian Zhuang
Shushui Wang
Zhiwei Zhang
Shaoying Zeng
Yunzhen Shi
Shaohan Nong
author_sort Jian Zhuang
collection DOAJ
description A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was based on electrocardiography and a cardiac computed tomography confirmed an ascending aortic aneurysm. Coronary angiography showed mural irregularity and a 50% constriction in the first diagonal artery. Following treatment with urokinase, corticosteroids, colchicine, and aspirin, most symptoms gradually improved. There were no complications noted at the one-year follow-up evaluation. Myocardial infarction is a rare event in children with Behçet's disease; treatment with corticosteroids and colchicine can result in regression of concomitant aneurysm.
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institution OA Journals
issn 0041-4301
2791-6421
language English
publishDate 2008-02-01
publisher Hacettepe University Institute of Child Health
record_format Article
series The Turkish Journal of Pediatrics
spelling doaj-art-1fef8cee4be4404d8c7c1e11648fc0852025-08-20T02:01:53ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212008-02-01501Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's diseaseJian Zhuang0Shushui WangZhiwei ZhangShaoying ZengYunzhen ShiShaohan NongDepartment of Pediatric Cardiology, Guangdong Provincial Cardiovascular Institute, Guangzhou, China. A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was based on electrocardiography and a cardiac computed tomography confirmed an ascending aortic aneurysm. Coronary angiography showed mural irregularity and a 50% constriction in the first diagonal artery. Following treatment with urokinase, corticosteroids, colchicine, and aspirin, most symptoms gradually improved. There were no complications noted at the one-year follow-up evaluation. Myocardial infarction is a rare event in children with Behçet's disease; treatment with corticosteroids and colchicine can result in regression of concomitant aneurysm. https://turkjpediatr.org/article/view/2387
spellingShingle Jian Zhuang
Shushui Wang
Zhiwei Zhang
Shaoying Zeng
Yunzhen Shi
Shaohan Nong
Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
The Turkish Journal of Pediatrics
title Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
title_full Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
title_fullStr Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
title_full_unstemmed Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
title_short Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease
title_sort acute myocardial infarction and ascending aortic aneurysm in a child with behcet s disease
url https://turkjpediatr.org/article/view/2387
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AT shushuiwang acutemyocardialinfarctionandascendingaorticaneurysminachildwithbehcetsdisease
AT zhiweizhang acutemyocardialinfarctionandascendingaorticaneurysminachildwithbehcetsdisease
AT shaoyingzeng acutemyocardialinfarctionandascendingaorticaneurysminachildwithbehcetsdisease
AT yunzhenshi acutemyocardialinfarctionandascendingaorticaneurysminachildwithbehcetsdisease
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