Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease

A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was b...

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Bibliographic Details
Main Authors: Jian Zhuang, Shushui Wang, Zhiwei Zhang, Shaoying Zeng, Yunzhen Shi, Shaohan Nong
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2008-02-01
Series:The Turkish Journal of Pediatrics
Online Access:https://turkjpediatr.org/article/view/2387
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Summary:A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was based on electrocardiography and a cardiac computed tomography confirmed an ascending aortic aneurysm. Coronary angiography showed mural irregularity and a 50% constriction in the first diagonal artery. Following treatment with urokinase, corticosteroids, colchicine, and aspirin, most symptoms gradually improved. There were no complications noted at the one-year follow-up evaluation. Myocardial infarction is a rare event in children with Behçet's disease; treatment with corticosteroids and colchicine can result in regression of concomitant aneurysm.
ISSN:0041-4301
2791-6421