Research progress of early biomarkers of hyperuricemia-induced renal injury
Hyperuricemia （HUA）-induced kidney injury has an insidious early onset and usually does not show clinical symptoms. Clinical indicators such as creatinine and urea nitrogen lack sensitivity and specificity in detecting early decline in kidney function， which are often detected only when the glomerul...
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| Format: | Article |
| Language: | zho |
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Editorial Department of Journal of Clinical Nephrology
2025-02-01
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| Series: | Linchuang shenzangbing zazhi |
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| Online Access: | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.02.010 |
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| author | Zeng Chui-ke Li Bing |
| author_facet | Zeng Chui-ke Li Bing |
| author_sort | Zeng Chui-ke |
| collection | DOAJ |
| description | Hyperuricemia （HUA）-induced kidney injury has an insidious early onset and usually does not show clinical symptoms. Clinical indicators such as creatinine and urea nitrogen lack sensitivity and specificity in detecting early decline in kidney function， which are often detected only when the glomerular filtration rate falls to half of the healthy level. At this time point， the kidney may have irreversible damage. Therefore， the search for early biomarkers associated with HUA-induced kidney injury is crucial for clinical intervention and prognosis. This article reviewed the research progress on the mechanism and early biomarkers of HUA-induced kidney injury. |
| format | Article |
| id | doaj-art-1fdd1b406014411a9014e1d84d2dfce5 |
| institution | DOAJ |
| issn | 1671-2390 |
| language | zho |
| publishDate | 2025-02-01 |
| publisher | Editorial Department of Journal of Clinical Nephrology |
| record_format | Article |
| series | Linchuang shenzangbing zazhi |
| spelling | doaj-art-1fdd1b406014411a9014e1d84d2dfce52025-08-20T03:12:48ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902025-02-0125215816310.3969/j.issn.1671-2390.2025.02.0101671-2390（2025）02-0158-06Research progress of early biomarkers of hyperuricemia-induced renal injuryZeng Chui-ke0Li Bing1Department of Nephrology， the Second Affiliated Hospital of Hainan Medical University， Haikou 570216， ChinaDepartment of Nephrology， the Second Affiliated Hospital of Hainan Medical University， Haikou 570216， ChinaHyperuricemia （HUA）-induced kidney injury has an insidious early onset and usually does not show clinical symptoms. Clinical indicators such as creatinine and urea nitrogen lack sensitivity and specificity in detecting early decline in kidney function， which are often detected only when the glomerular filtration rate falls to half of the healthy level. At this time point， the kidney may have irreversible damage. Therefore， the search for early biomarkers associated with HUA-induced kidney injury is crucial for clinical intervention and prognosis. This article reviewed the research progress on the mechanism and early biomarkers of HUA-induced kidney injury.http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.02.010hyperuricemiakidney injurybiomarkers |
| spellingShingle | Zeng Chui-ke Li Bing Research progress of early biomarkers of hyperuricemia-induced renal injury Linchuang shenzangbing zazhi hyperuricemia kidney injury biomarkers |
| title | Research progress of early biomarkers of hyperuricemia-induced renal injury |
| title_full | Research progress of early biomarkers of hyperuricemia-induced renal injury |
| title_fullStr | Research progress of early biomarkers of hyperuricemia-induced renal injury |
| title_full_unstemmed | Research progress of early biomarkers of hyperuricemia-induced renal injury |
| title_short | Research progress of early biomarkers of hyperuricemia-induced renal injury |
| title_sort | research progress of early biomarkers of hyperuricemia induced renal injury |
| topic | hyperuricemia kidney injury biomarkers |
| url | http://www.lcszb.com/article/doi/10.3969/j.issn.1671-2390.2025.02.010 |
| work_keys_str_mv | AT zengchuike researchprogressofearlybiomarkersofhyperuricemiainducedrenalinjury AT libing researchprogressofearlybiomarkersofhyperuricemiainducedrenalinjury |