Neoadjuvant Immunotherapy in Head and Neck Cancers: A Paradigm Shift in Treatment Approach

Neoadjuvant Immunotherapy in Head and Neck Cancers: A Paradigm Shift in Treatment Approach

Checkpoint inhibitors (ICIs) have demonstrated substantial efficacy in the treatment of numerous solid tumors, including head and neck cancer. Their inclusion in the therapeutic paradigm in metastatic lines of treatment has certainly improved the outcomes of these patients. Starting from this assump...

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Main Authors: Alessia Zotta, Maria Luisa Marciano, Francesco Sabbatino, Alessandro Ottaiano, Marco Cascella, Monica Pontone, Massimo Montano, Ester Calogero, Francesco Longo, Morena Fasano, Teresa Troiani, Fortunato Ciardiello, Fabiana Raffaella Rampetta, Giovanni Salzano, Giovanni Dell’Aversana Orabona, Luigi Califano, Franco Ionna, Francesco Perri
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Biomedicines
Subjects:
immunotherapy
neoadjuvant
checkpoint inhibitors
head and neck squamous cell carcinoma
tumor mutational burden
Online Access:https://www.mdpi.com/2227-9059/12/10/2337
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