Insights into the Silylation of Benzodiazepines Using <i>N</i>,<i>O</i>-Bis(trimethylsilyl)trifluoroacetamide (BSTFA): In Search of Optimal Conditions for Forensic Analysis by GC-MS

Insights into the Silylation of Benzodiazepines Using <i>N</i>,<i>O</i>-Bis(trimethylsilyl)trifluoroacetamide (BSTFA): In Search of Optimal Conditions for Forensic Analysis by GC-MS

Silylation is a widely used derivatization technique for the gas chromatographic analysis of benzodiazepines, a class of psychoactive drugs commonly encountered in forensic and biological samples. This study investigated the optimal experimental conditions for the silylation of benzodiazepines using...

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Bibliographic Details
Main Authors: Eleazar Vargas Mena, Eliana R. Herrera Giraldo, Jovanny A. Gómez Castaño
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Molecules
Subjects:
benzodiazepine analysis
forensic toxicology
gas chromatography-mass spectrometry
silylation derivatization
designer benzodiazepines
BSTFA
Online Access:https://www.mdpi.com/1420-3049/29/24/5884
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