ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

ROS‐Responsive Microneedle Patches Enable Peri‐Lacrimal Gland Therapeutic Administration for Long‐Acting Therapy of Sjögren's Syndrome‐Related Dry Eye

Abstract Sjögren's syndrome‐related dry eye (SSDE) is a severe dry eye subtype characterized by significant immune cell attacks on the lacrimal gland. However, delivering immunosuppressive drugs to the lacrimal glands for SSDE therapy safely and sustainably poses significant challenges in clini...

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Bibliographic Details
Main Authors: Jingqing Mu, Xiangyu Ding, Yapeng Song, Baoyue Mi, Xiaolong Fang, Baihua Chen, Bin Yao, Xuguang Sun, Xiaoyong Yuan, Shutao Guo, Xia Hua
Format: Article
Language:English
Published: Wiley 2025-04-01
Series:Advanced Science
Subjects:
drug delivery
dry eye
immunosuppression
microneedle
sustained release
Online Access:https://doi.org/10.1002/advs.202409562
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