Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults
<b>Objective:</b> This study aimed to measure changes in preferences regarding health-related quality of life associated with COVID-19 and RSV illness in children and adults from 2021 (during the COVID-19 pandemic) to 2023 (post-pandemic). <b>Methods:</b> A stated-preference...
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MDPI AG
2025-01-01
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| Online Access: | https://www.mdpi.com/2227-9067/12/2/181 |
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| author | Kerra R. Mercon Angela M. Rose Christopher J. Cadham Acham Gebremariam Jamison Pike Eve Wittenberg Lisa A. Prosser |
| author_facet | Kerra R. Mercon Angela M. Rose Christopher J. Cadham Acham Gebremariam Jamison Pike Eve Wittenberg Lisa A. Prosser |
| author_sort | Kerra R. Mercon |
| collection | DOAJ |
| description | <b>Objective:</b> This study aimed to measure changes in preferences regarding health-related quality of life associated with COVID-19 and RSV illness in children and adults from 2021 (during the COVID-19 pandemic) to 2023 (post-pandemic). <b>Methods:</b> A stated-preference survey elicited time trade-off (TTO) values from US adults in spring 2021 (<i>n</i> = 1014) and summer 2023 (<i>n</i> = 1186). Respondents were asked to indicate how much time they would hypothetically be willing to trade from the end of their life to avoid the effects of varying severities of COVID-19 and RSV illness for: (1) children; (2) parents of an ill child (family spillover); and (3) adults. Attitudes relating to COVID-19 vaccination and data on experience with COVID-19 or RSV illness were also collected. The primary outcome measure was the loss in quality-adjusted life years (QALYs). Changes in preferences over the time period from 2021 to 2023 were evaluated using regression analysis. <b>Results:</b> QALY losses increased with disease severity and were highest for Long COVID. Across all COVID-19 and RSV health states, QALY losses associated with child health states were higher than family spillover or adult health states. In the regression analysis, QALY losses reported in the 2023 survey were significantly lower than 2021 QALY losses for COVID-19, but not RSV. <b>Conclusions:</b> Preferences may change over time in a pandemic context and therefore, economic analyses of pandemic interventions should consider the timeframe of health preference data collection to determine whether they are suitable to include in an economic evaluation. Even with the impacts on health-related quality of life attenuated over time, childhood illnesses still had a measurable impact on caregivers’ quality of life. |
| format | Article |
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| institution | DOAJ |
| issn | 2227-9067 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-1fb53cf9489548bcbfb1c70e306819be2025-08-20T02:44:34ZengMDPI AGChildren2227-90672025-01-0112218110.3390/children12020181Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and AdultsKerra R. Mercon0Angela M. Rose1Christopher J. Cadham2Acham Gebremariam3Jamison Pike4Eve Wittenberg5Lisa A. Prosser6Susan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI 48109, USASusan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI 48109, USADepartment of Health Management and Policy, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USASusan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI 48109, USACenters for Disease Control and Prevention, Atlanta, GA 30333, USACenter for Health Decision Science, Harvard T. H. Chan School of Public Health, Boston, MA 02115, USASusan B. Meister Child Health Evaluation and Research Center, University of Michigan, Ann Arbor, MI 48109, USA<b>Objective:</b> This study aimed to measure changes in preferences regarding health-related quality of life associated with COVID-19 and RSV illness in children and adults from 2021 (during the COVID-19 pandemic) to 2023 (post-pandemic). <b>Methods:</b> A stated-preference survey elicited time trade-off (TTO) values from US adults in spring 2021 (<i>n</i> = 1014) and summer 2023 (<i>n</i> = 1186). Respondents were asked to indicate how much time they would hypothetically be willing to trade from the end of their life to avoid the effects of varying severities of COVID-19 and RSV illness for: (1) children; (2) parents of an ill child (family spillover); and (3) adults. Attitudes relating to COVID-19 vaccination and data on experience with COVID-19 or RSV illness were also collected. The primary outcome measure was the loss in quality-adjusted life years (QALYs). Changes in preferences over the time period from 2021 to 2023 were evaluated using regression analysis. <b>Results:</b> QALY losses increased with disease severity and were highest for Long COVID. Across all COVID-19 and RSV health states, QALY losses associated with child health states were higher than family spillover or adult health states. In the regression analysis, QALY losses reported in the 2023 survey were significantly lower than 2021 QALY losses for COVID-19, but not RSV. <b>Conclusions:</b> Preferences may change over time in a pandemic context and therefore, economic analyses of pandemic interventions should consider the timeframe of health preference data collection to determine whether they are suitable to include in an economic evaluation. Even with the impacts on health-related quality of life attenuated over time, childhood illnesses still had a measurable impact on caregivers’ quality of life.https://www.mdpi.com/2227-9067/12/2/181preference valuationCOVID-19RSVpediatricstime trade-offQALYs |
| spellingShingle | Kerra R. Mercon Angela M. Rose Christopher J. Cadham Acham Gebremariam Jamison Pike Eve Wittenberg Lisa A. Prosser Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults Children preference valuation COVID-19 RSV pediatrics time trade-off QALYs |
| title | Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults |
| title_full | Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults |
| title_fullStr | Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults |
| title_full_unstemmed | Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults |
| title_short | Health Preferences in Transition: Differences from Pandemic to Post-Pandemic in Valuation of COVID-19 and RSV Illness in Children and Adults |
| title_sort | health preferences in transition differences from pandemic to post pandemic in valuation of covid 19 and rsv illness in children and adults |
| topic | preference valuation COVID-19 RSV pediatrics time trade-off QALYs |
| url | https://www.mdpi.com/2227-9067/12/2/181 |
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