Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience
Background/Aim. Serrated polyposis syndrome (SPS) is a rare condition characterized by multiple serrated polyps throughout the colon and rectum. The aim of this study was to evaluate the clinicopathological characteristics of SPS in Koreans. Methods. This retrospective analysis of prospectively coll...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2015/842876 |
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| author | Hyung-Keun Kim Kyung-Jin Seo Hyun Ho Choi Sung Soo Kim Hiun-Suk Chae Ok-Ran Shin Chang Hyuck Ahn Young-Seok Cho |
| author_facet | Hyung-Keun Kim Kyung-Jin Seo Hyun Ho Choi Sung Soo Kim Hiun-Suk Chae Ok-Ran Shin Chang Hyuck Ahn Young-Seok Cho |
| author_sort | Hyung-Keun Kim |
| collection | DOAJ |
| description | Background/Aim. Serrated polyposis syndrome (SPS) is a rare condition characterized by multiple serrated polyps throughout the colon and rectum. The aim of this study was to evaluate the clinicopathological characteristics of SPS in Koreans. Methods. This retrospective analysis of prospectively collected data was performed using information from the endoscopy, clinical records, and pathology database system of Uijeongbu St. Mary’s Hospital. Consecutive patients satisfying the updated 2010 World Health Organization criteria for SPS between June 2011 and May 2014 were enrolled. Results. Of the 17,552 patients who underwent colonoscopies during the study period, 11 (0.06%) met the criteria for SPS. The mean age of these patients was 55.6 years. Ten patients (91%) were males. None had a family history of CRC or a first-degree relative with SPS. Seven patients (64%) had synchronous advanced adenoma. One patient had coexistence of SPS with CRC that was diagnosed at the initial colonoscopy. Five patients (45%) had more than 30 serrated polyps. One of the patients underwent surgery and 10 underwent endoscopic resection. Conclusion. The prevalence of SPS in this study cohort was comparable to that in Western populations. Considering the high risk of CRC, correct diagnosis and careful follow-up for SPS are necessary. |
| format | Article |
| id | doaj-art-1fb33afa7bbe400d9680d37e277d6dff |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-1fb33afa7bbe400d9680d37e277d6dff2025-02-03T05:43:53ZengWileyGastroenterology Research and Practice1687-61211687-630X2015-01-01201510.1155/2015/842876842876Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center ExperienceHyung-Keun Kim0Kyung-Jin Seo1Hyun Ho Choi2Sung Soo Kim3Hiun-Suk Chae4Ok-Ran Shin5Chang Hyuck Ahn6Young-Seok Cho7Department of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Hospital Pathology, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Hospital Pathology, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of General Surgery, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaDepartment of Internal Medicine, Uijeongbu St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Uijeongbu 480-717, Republic of KoreaBackground/Aim. Serrated polyposis syndrome (SPS) is a rare condition characterized by multiple serrated polyps throughout the colon and rectum. The aim of this study was to evaluate the clinicopathological characteristics of SPS in Koreans. Methods. This retrospective analysis of prospectively collected data was performed using information from the endoscopy, clinical records, and pathology database system of Uijeongbu St. Mary’s Hospital. Consecutive patients satisfying the updated 2010 World Health Organization criteria for SPS between June 2011 and May 2014 were enrolled. Results. Of the 17,552 patients who underwent colonoscopies during the study period, 11 (0.06%) met the criteria for SPS. The mean age of these patients was 55.6 years. Ten patients (91%) were males. None had a family history of CRC or a first-degree relative with SPS. Seven patients (64%) had synchronous advanced adenoma. One patient had coexistence of SPS with CRC that was diagnosed at the initial colonoscopy. Five patients (45%) had more than 30 serrated polyps. One of the patients underwent surgery and 10 underwent endoscopic resection. Conclusion. The prevalence of SPS in this study cohort was comparable to that in Western populations. Considering the high risk of CRC, correct diagnosis and careful follow-up for SPS are necessary.http://dx.doi.org/10.1155/2015/842876 |
| spellingShingle | Hyung-Keun Kim Kyung-Jin Seo Hyun Ho Choi Sung Soo Kim Hiun-Suk Chae Ok-Ran Shin Chang Hyuck Ahn Young-Seok Cho Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience Gastroenterology Research and Practice |
| title | Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience |
| title_full | Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience |
| title_fullStr | Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience |
| title_full_unstemmed | Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience |
| title_short | Clinicopathological Characteristics of Serrated Polyposis Syndrome in Korea: Single Center Experience |
| title_sort | clinicopathological characteristics of serrated polyposis syndrome in korea single center experience |
| url | http://dx.doi.org/10.1155/2015/842876 |
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