Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis
Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/39 |
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| author | E. V. Esaulenko O. E. Nikitina N. V. Dunaeva A. N. Uskov T. L. Mogilevets |
| author_facet | E. V. Esaulenko O. E. Nikitina N. V. Dunaeva A. N. Uskov T. L. Mogilevets |
| author_sort | E. V. Esaulenko |
| collection | DOAJ |
| description | Patients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes. |
| format | Article |
| id | doaj-art-1fadd4cb9a1a4c93809afcd711e44447 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-1fadd4cb9a1a4c93809afcd711e444472025-08-20T03:44:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0133424510.22625/2072-6732-2011-3-3-42-4553Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitisE. V. Esaulenko0O. E. Nikitina1N. V. Dunaeva2A. N. Uskov3T. L. Mogilevets4Saint-Petersburg State Pediatric Medical Academy, Saint-PetersburgResearch Institute of Influenza, Saint-PetersburgResearch Institute of Influenza, Saint-PetersburgResearch Institute of Children Infection Diseases FMBA of Russia, Saint-PetersburgYaroslav-the-Wise Novgorod State University, Velikiy NovgorodPatients with chronic virus hepatitis (32 patients, 13 with chronic hepatitis B and 19 with chronic hepatitis C) ages from 20 to 72 with elevated levels of bilirubin and active alanine aminotransferase, aspartate aminotransferase, gamma- glutamyl transpeptidase, received ursodeoxycholic acid (Urdoxa) over the course of 12 weeks. During therapy alanine aminotransferase, aspartate aminotransferase, bilirubin and gamma-glutamyl transpeptidase levels decreased. Urdoxa demonstrated good tolerance, efficacy and no visible side effects. Thus, Urdoxa could be used in treatment of chronic viral hepatitis with cytolytic and cholestatic syndromes.https://journal.niidi.ru/jofin/article/view/39chronic viral hepatitisursodeoxycholic acidurdoxa |
| spellingShingle | E. V. Esaulenko O. E. Nikitina N. V. Dunaeva A. N. Uskov T. L. Mogilevets Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis Журнал инфектологии chronic viral hepatitis ursodeoxycholic acid urdoxa |
| title | Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis |
| title_full | Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis |
| title_fullStr | Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis |
| title_full_unstemmed | Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis |
| title_short | Clinical experience with ursodeoxycholic acid (Urdoxa) in complex therapy of chronic viral hepatitis |
| title_sort | clinical experience with ursodeoxycholic acid urdoxa in complex therapy of chronic viral hepatitis |
| topic | chronic viral hepatitis ursodeoxycholic acid urdoxa |
| url | https://journal.niidi.ru/jofin/article/view/39 |
| work_keys_str_mv | AT evesaulenko clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis AT oenikitina clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis AT nvdunaeva clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis AT anuskov clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis AT tlmogilevets clinicalexperiencewithursodeoxycholicacidurdoxaincomplextherapyofchronicviralhepatitis |