Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review
Juvenile idiopathic arthritis (JIA) associated uveitis is the most common extra-articular manifestation of JIA. Nowadays, unified approach for the management of this condition has been developed despite all the difficulties in diagnosis. It allows to avoid many long-term complications and improves p...
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| Format: | Article |
| Language: | English |
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"Paediatrician" Publishers LLC
2025-07-01
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| Series: | Вопросы современной педиатрии |
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| Online Access: | https://vsp.spr-journal.ru/jour/article/view/3773 |
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| author | Alexandr A. Yakovlev Tatiana N. Nikitina Mikhail M. Kostik |
| author_facet | Alexandr A. Yakovlev Tatiana N. Nikitina Mikhail M. Kostik |
| author_sort | Alexandr A. Yakovlev |
| collection | DOAJ |
| description | Juvenile idiopathic arthritis (JIA) associated uveitis is the most common extra-articular manifestation of JIA. Nowadays, unified approach for the management of this condition has been developed despite all the difficulties in diagnosis. It allows to avoid many long-term complications and improves patients’ quality of life. Rapid development of pharmacotherapy (including appearance of new immunosuppressive and genetically engineered biologic drugs) expands the therapeutic methods and increases the chances in achieving sustained remission. However, still there are many questions regarding genetically engineered biologic drugs safety, optimal time to treatment cessation, and long-term follow-up in patients with JIA. This review summarizes and analyzes modern data regarding treatment approaches, therapy efficacy and safety, and perspectives for managing patients with uveitis and JIA. |
| format | Article |
| id | doaj-art-1fac07716e4e484fa465eb7410d4aa4c |
| institution | Kabale University |
| issn | 1682-5527 1682-5535 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | "Paediatrician" Publishers LLC |
| record_format | Article |
| series | Вопросы современной педиатрии |
| spelling | doaj-art-1fac07716e4e484fa465eb7410d4aa4c2025-08-20T03:34:42Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352025-07-0124316217710.15690/vsp.v24i3.29102236Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative ReviewAlexandr A. Yakovlev0Tatiana N. Nikitina1Mikhail M. Kostik2Saint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversityJuvenile idiopathic arthritis (JIA) associated uveitis is the most common extra-articular manifestation of JIA. Nowadays, unified approach for the management of this condition has been developed despite all the difficulties in diagnosis. It allows to avoid many long-term complications and improves patients’ quality of life. Rapid development of pharmacotherapy (including appearance of new immunosuppressive and genetically engineered biologic drugs) expands the therapeutic methods and increases the chances in achieving sustained remission. However, still there are many questions regarding genetically engineered biologic drugs safety, optimal time to treatment cessation, and long-term follow-up in patients with JIA. This review summarizes and analyzes modern data regarding treatment approaches, therapy efficacy and safety, and perspectives for managing patients with uveitis and JIA.https://vsp.spr-journal.ru/jour/article/view/3773uveitisiridocyclitisjuvenile idiopathic arthritistherapygenetically engineered biologic drugsanti-tumor necrosis factor alpha antibodies |
| spellingShingle | Alexandr A. Yakovlev Tatiana N. Nikitina Mikhail M. Kostik Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review Вопросы современной педиатрии uveitis iridocyclitis juvenile idiopathic arthritis therapy genetically engineered biologic drugs anti-tumor necrosis factor alpha antibodies |
| title | Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review |
| title_full | Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review |
| title_fullStr | Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review |
| title_full_unstemmed | Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review |
| title_short | Juvenile Idiopathic Arthritis Associated Uveitis. Modern Therapy Approaches: Narrative Review |
| title_sort | juvenile idiopathic arthritis associated uveitis modern therapy approaches narrative review |
| topic | uveitis iridocyclitis juvenile idiopathic arthritis therapy genetically engineered biologic drugs anti-tumor necrosis factor alpha antibodies |
| url | https://vsp.spr-journal.ru/jour/article/view/3773 |
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