A diffusion MRI model for random walks confined on cylindrical surfaces: towards non-invasive quantification of myelin sheath radius

A diffusion MRI model for random walks confined on cylindrical surfaces: towards non-invasive quantification of myelin sheath radius

IntroductionQuantifying the myelin sheath radius of myelinated axons in vivo is important for understanding, diagnosing, and monitoring various neurological disorders. Despite advancements in diffusion MRI (dMRI) microstructure techniques, there are currently no models specifically designed to estim...

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Bibliographic Details
Main Authors: Erick J. Canales-Rodríguez, Chantal M. W. Tax, Elda Fischi-Gomez, Derek K. Jones, Jean-Philippe Thiran, Jonathan Rafael-Patiño
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Physics
Subjects:
diffusion MRI
myelin water
Monte Carlo simulations
white matter microstructure
myelin sheath radius
Online Access:https://www.frontiersin.org/articles/10.3389/fphy.2025.1516630/full
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