Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study

Background and Aims: Palatoplasties are extremely painful surgeries commonly performed in children; hence, providing excellent analgesia for these surgeries is crucial. This study aims to evaluate the effect of bilateral intranasal transmucosal sphenopalatine ganglion (SPG) block on intraoperative f...

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Main Authors: Yellala Srinivas, Shubhi Singhal, Rupesh Yadav, Devang Bharti
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-05-01
Series:Indian Journal of Anaesthesia
Subjects:
Online Access:https://journals.lww.com/10.4103/ija.ija_1186_24
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author Yellala Srinivas
Shubhi Singhal
Rupesh Yadav
Devang Bharti
author_facet Yellala Srinivas
Shubhi Singhal
Rupesh Yadav
Devang Bharti
author_sort Yellala Srinivas
collection DOAJ
description Background and Aims: Palatoplasties are extremely painful surgeries commonly performed in children; hence, providing excellent analgesia for these surgeries is crucial. This study aims to evaluate the effect of bilateral intranasal transmucosal sphenopalatine ganglion (SPG) block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia (GA). Methods: Thirty American Society of Anesthesiologists physical status (PS) I and II patients, aged 6 months–12 years, scheduled to undergo palatoplasty, were randomised to two groups. After induction of anaesthesia, patients in Group T received bilateral SPG block using 0.5% bupivacaine-soaked cotton-tip applicators, while patients in Group C received standard anaesthesia care. The primary outcome was intraoperative fentanyl requirement, and secondary outcomes were intraoperative haemodynamics and post-extubation Paediatric Anaesthesia Emergence Delirium (PAED) scale scores at 5 and 10 min, respectively. Results: The mean intraoperative fentanyl consumption was 26.73 [standard deviation (SD): 10.19)] [95% confidence interval (CI): 20.38, 33.08] μg in Group T compared to 34.47 (SD: 12.73) (95% CI: 27.20, 41.74) μg in Group C (P = 0.008). Heart rate and mean arterial pressure were lower in Group T as compared to that in Group C (P < 0.05). PAED scale scores were recorded to be 7.33 (SD: 1.50) (95% CI: 6.47, 8.19) and 6.00 (SD: 1.31) (95% CI: 5.30, 6.70) for Group T, and 15.53 (SD: 0.74) (95% CI: 15.13, 15.93) and 14.07 (SD: 0.59) (95% CI: 13.75, 14.39) for Group C at 5 and 10 min, respectively (P < 0.001). Conclusion: SPG block causes a significant reduction in intraoperative fentanyl consumption, stabilises haemodynamics, and facilitates smoother recovery of children undergoing palatoplasty under GA.
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spelling doaj-art-1fa12c8472fd4a4baa2235f5bbdc117d2025-08-20T03:52:16ZengWolters Kluwer Medknow PublicationsIndian Journal of Anaesthesia0019-50490976-28172025-05-0169547147610.4103/ija.ija_1186_24Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative studyYellala SrinivasShubhi SinghalRupesh YadavDevang BhartiBackground and Aims: Palatoplasties are extremely painful surgeries commonly performed in children; hence, providing excellent analgesia for these surgeries is crucial. This study aims to evaluate the effect of bilateral intranasal transmucosal sphenopalatine ganglion (SPG) block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia (GA). Methods: Thirty American Society of Anesthesiologists physical status (PS) I and II patients, aged 6 months–12 years, scheduled to undergo palatoplasty, were randomised to two groups. After induction of anaesthesia, patients in Group T received bilateral SPG block using 0.5% bupivacaine-soaked cotton-tip applicators, while patients in Group C received standard anaesthesia care. The primary outcome was intraoperative fentanyl requirement, and secondary outcomes were intraoperative haemodynamics and post-extubation Paediatric Anaesthesia Emergence Delirium (PAED) scale scores at 5 and 10 min, respectively. Results: The mean intraoperative fentanyl consumption was 26.73 [standard deviation (SD): 10.19)] [95% confidence interval (CI): 20.38, 33.08] μg in Group T compared to 34.47 (SD: 12.73) (95% CI: 27.20, 41.74) μg in Group C (P = 0.008). Heart rate and mean arterial pressure were lower in Group T as compared to that in Group C (P < 0.05). PAED scale scores were recorded to be 7.33 (SD: 1.50) (95% CI: 6.47, 8.19) and 6.00 (SD: 1.31) (95% CI: 5.30, 6.70) for Group T, and 15.53 (SD: 0.74) (95% CI: 15.13, 15.93) and 14.07 (SD: 0.59) (95% CI: 13.75, 14.39) for Group C at 5 and 10 min, respectively (P < 0.001). Conclusion: SPG block causes a significant reduction in intraoperative fentanyl consumption, stabilises haemodynamics, and facilitates smoother recovery of children undergoing palatoplasty under GA.https://journals.lww.com/10.4103/ija.ija_1186_24airway extubationanalgesiaanaesthesiabupivacaineemergence deliriumfentanylpalatoplastysphenopalatine ganglion block
spellingShingle Yellala Srinivas
Shubhi Singhal
Rupesh Yadav
Devang Bharti
Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
Indian Journal of Anaesthesia
airway extubation
analgesia
anaesthesia
bupivacaine
emergence delirium
fentanyl
palatoplasty
sphenopalatine ganglion block
title Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
title_full Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
title_fullStr Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
title_full_unstemmed Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
title_short Effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia – A randomised, double-blinded, comparative study
title_sort effect of bilateral intranasal transmucosal sphenopalatine ganglion block on intraoperative fentanyl requirement in children undergoing palatoplasty under general anaesthesia a randomised double blinded comparative study
topic airway extubation
analgesia
anaesthesia
bupivacaine
emergence delirium
fentanyl
palatoplasty
sphenopalatine ganglion block
url https://journals.lww.com/10.4103/ija.ija_1186_24
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